From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot +3 more
wiley +1 more source
Multiport Semi-Dual Active Bridge Converter
openaire +1 more source
A Scalable Microservices Architecture for Condition Monitoring and State-of-Health Tracking in Power Conversion Systems. [PDF]
García-Campos JM +4 more
europepmc +1 more source
Barrier‐Assisted Plasma Doping for Spatially Selective Resistance Engineering in MoS2 Transistors
Barrier‐assisted NH3 plasma doping enables damage‐free, spatially selective carrier modulation in monolayer MoS2 transistors. An ultrathin pV3D3/Al2O3 protective‐dielectric stack acts as a chemical filter that allows NHx radicals to reach the MoS2 surface while blocking plasma damage. This process achieves a high electron concentration of 4.3 × 1013 cm−
Inseong Lee +15 more
wiley +1 more source
A total loss minimization modulation for series-resonant dual-active-bridge dc-dc converter with triple phase shift control. [PDF]
Zhou S, Wang J, Tang J.
europepmc +1 more source
Sub‐stoichiometric amounts of Na+ or K+ enhance defect healing during Silicalite‐1 (MFI) and TS‐1 calcination by promoting Si–O–Si annealing and healing framework vacancies. The resulting defect‐free zeolites are more hydrophobic and show improved butanol/water separation and improved activity and selectivity in the epoxidation of 1‐hexene, offering a ...
Christos Kanteler +14 more
wiley +1 more source
Fuzzy logic sliding mode controller based solar PV fed UPQC for improvement of dynamic performance and power quality enhancement in distribution power system. [PDF]
Sravanthi G, Rosalina KM, Reddy TRS.
europepmc +1 more source
The transition from cryogenic distillation to polymeric sorbents for light hydrocarbon purification is crucial for energy and environmental sustainability. The polymeric sorbents are engineered to separate gas mixtures based on their specific properties.
Kelechi Festus +9 more
wiley +1 more source
Cooperative modular multilevel converter control based on PSO-optimized fuzzy-PI and hierarchical finite-state model predictive control. [PDF]
Liu Y, Tian Y, Zhang W, Wang Y.
europepmc +1 more source
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi +5 more
wiley +1 more source

