Results 121 to 130 of about 803,363 (301)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Dual‐band single‐layer substrate‐integrated waveguide filtering antennas with independently controllable bands

IET Microwaves, Antennas & Propagation
A novel design method of dual‐band single‐layer substrate‐integrated waveguide (SIW) filtering antennas with independently controllable bands is proposed in this paper. The basic two‐pole dual‐band filtering antenna is proposed by a dual‐mode rectangular
Ke Gong, Jia Liu, Chunfeng Fan, Xuehui Hu, Jintu Sun, Yan Liu, Shuang Chen, Qing Liu   +7 more
doaj   +1 more source

Spectral control of broadband light through random media by wavefront shaping

, 2012
A random medium can serve as a controllable arbitrary spectral filter with spectral resolution determined by the inverse of the interaction time of the light in the medium.
Aulbach, Conkey, Eran Small, Fink, Freund, Freund, Katz, Katz, Kohlgraf-Owens, Lemoult, Lerosey, McCabe, Mosk, Ori Katz, Popoff, Popoff, Small, Svensson, van Beijnum, Vellekoop, Vellekoop, Yaqoob, Yaron Silberberg, Yefeng Guan   +23 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Dual-band transmission polarization conversion metasurface and its reconfigurable-phase design

Results in Physics
Although abundant transmission polarization conversion metasurfaces (T-PCMs) have been reported, a dual-band T-PCM has only received little attention. Moreover, a reconfigurable-phase design of the T-PCMs is limited to a single-frequency band operation ...
Zexu Guo, Yulong Zhou, Huanhuan Yang, Sijia Li, Tong Li, Xiangyu Cao   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Design and simulated characterization of the dual-band polarizer based on metasurface structure

AIP Advances
Dual-band polarizers must simultaneously exhibit high transmittance and bandwidth efficiency in fields such as polarization navigation and efficient detection. However, in most studies, the detection of dual bands is inefficient.
Hangwei Zhu, Yanlin He, Shuning Wang, Lidan Lu, Lianqing Zhu   +4 more
doaj   +1 more source

Reflex feed system for dual frequency antenna with frequency cutoff means [PDF]

, 1978
A reflex feed system is described for a dual frequency antenna such as one which transmits and receives both S and X band signals. The dichroic plate, normally employed for directing X band radiation away from the X band horn, is replaced by a flange ...
Hartop, R. W.
core   +1 more source

Dual-Band and Dual-Polarized Antenna System Design for Ka-Band Applications

2024 IEEE International Symposium on Antennas and Propagation and INC/USNC‐URSI Radio Science Meeting (AP-S/INC-USNC-URSI)
This study presents a dual-band dual-circular polarization feed chain for Ka-band applications such as satellite communication systems. The proposed feed chain consists of a Tx-Rx corrugated antenna, iris polarizer, rectangular-to-square transition, and square-to- circular transition.
Guvenc, Merve, Sisman, Ismail, Ergin, A. Arif   +2 more
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source