Results 51 to 60 of about 185,058 (261)

A Dual Band Branch Line Coupler With Wide Frequency Ratio

IEEE Access, 2019
A dual-band quadrature branch line coupler (BLC) with wide frequency ratio has been proposed in this paper. A dual-band quarter wave (λ/4) transmission line structure with wide frequency ratio operation has also been presented here with closed ...
Aijaz M. Zaidi, Mirza Tariq Beg, Binod K. Kanaujia, Kunal Srivastava, Karumudi Rambabu   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Four-Port Dual-Band Dual-Polarized Antenna for Ku-Band Satellite Communications

Applied Sciences
This paper presents the development of a four-port dual-band dual-polarized antenna for transmitting/receiving (Tx/Rx) applications in Ku-band satellite communications.
Son Trinh-Van, Woo Yong Yang, Hyung Won Cho, Keum Cheol Hwang   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dual-band X/Ku Reflectarray Antenna Using a Novel FSS-Backed Unit-Cell with Quasi-Spiral Phase Delay Line

Journal of Microwaves, Optoelectronics and Electromagnetic Applications
A novel FSS-Backed reflectarray unit cell is introduced to design a dual-band X/Ku Reflectarray Antenna (RA). A Ku-band RA based on this FSS-Backed cell element is designed and located on the top of a conventional X-band RA.
Iman Derafshi, Nader Komjani, Ensieh Ghasemi-Mizuji, Mohammad Mohammadirad   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Integrated Dual-Band Filtering/Duplexing Antennas

IEEE Access, 2018
In this paper, the state-of-the-art integrated filtering antennas with dual-band operation are first reviewed. Then, two designs of dual-band microstrip filtering antennas with a low-frequency ratio are presented.
Chun-Xu Mao, Steven Gao, Yi Wang, Ying Liu, Xue-Xia Yang, Zhi-Qun Cheng, You-Lin Geng   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Ultra-Thin Metasheet for Dual-Wide-Band Linear to Circular Polarization Conversion With Wide-Angle Performance

IEEE Access, 2020
Satellite communication systems require dual-band circularly polarized (CP) waves to integrate receiving and transmit antennas into one dual-band terminal. Polarization converters play an important role in such a scenario to convert the incoming linearly
Ayesha Kosar Fahad, Cunjun Ruan, Rabia Nazir, Muhammad Saleem, Tanveer Ul Haq, Shahid Ullah, Wenlong He   +6 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source