Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
A complementary descriptor for elucidating selective PMS activation by iron single-atom catalysts with tunable interatomic distances. [PDF]
Wang Y +10 more
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
PIR-SBFR: A Calibration-Free Sensor-to-Inference Routing Interface for Aerial Optical Object Detection. [PDF]
Wang Z +6 more
europepmc +1 more source
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Mol2Image: an enhanced DDI prediction framework leveraging drug molecular descriptors. [PDF]
Helmy N, Maghawry HA, Badr N.
europepmc +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
Phase-PCANet for Fingerprint Image Liveness Detection. [PDF]
Li J, Wang X.
europepmc +1 more source
Phase-Resolved Dual Control of Phenol Photodissociation at the Air-Water Interface From Structure-Resolved Statistics. [PDF]
Yin Q +8 more
europepmc +1 more source
Machine Learning-Driven Prediction of Dose-Linear Pharmacokinetics: Utilizing Molecular Descriptors to Guide Formulation Strategy. [PDF]
Levy ES, Samy KE, Anelli A, Leung DH.
europepmc +1 more source

