Results 241 to 250 of about 974,940 (289)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Molecular contrastive learning with graph attention network (MoCL-GAT) for enhanced molecular representation. [PDF]

BMC Bioinformatics
Dalkıran A, Rifaioglu AS, Cetin-Atalay R, Acar AC, Doğan T, Atalay MV.   +5 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

MLHNet-Lung: an attention-guided multi-level CNN-transformer fusion framework with CBAM and GeM pooling for explainable multiclass lung CT image classification. [PDF]

Front Med (Lausanne)
Hanif F, Ahmed AET, Raza A.
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Positional Isomers of B₆C₆N₆ Nanorings: Stability, Reactivity, and Optical Properties from First Principles. [PDF]

Nanomaterials (Basel)
Chen X, Li P, Gong S.
europepmc   +1 more source

When Does Machine Learning Add Value over Theory? Predicting API Solubility in Binary Mixtures with COSMO-RS and DOOIT2 Across Diverse and Homogeneous Systems. [PDF]

Molecules
Przybyłek M, Jeliński T, Drużyński A, Cysewski P.   +3 more
europepmc   +1 more source

DDHTS-Net: dual-domain hierarchical texture supervision network for plant texture analysis. [PDF]

Front Plant Sci
Li B, Guo E, Xu X, Wu QMJ.
europepmc   +1 more source

SREF: Semantics-Refined Feature Extraction for Long-Term Visual Localization. [PDF]

J Imaging
Wu D, Zhu K, Shi H, Zhou F, Kuang M.
europepmc   +1 more source

Prediction of intrinsic solubility for drug-like organic compounds using automated network optimizer (ANO) for physicochemical feature and hyperparameter optimization. [PDF]

J Cheminform
Chung YK, Lee SJ, Lee J, Cho H, Kim SJ, Huh J.   +5 more
europepmc   +1 more source