Results 101 to 110 of about 488,497 (353)

Enhanced colour encoding of materials discrimination information for multiple view dual-energy x-ray imaging

open access: yes, 2009
This thesis reports an investigation into dual-energy X-ray discrimination techniques. These techniques are designed to provide colour-coded materials discrimination information in a sequence of perspective images exhibiting sequential parallax.
Wang, X
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

PATIENT SPECIFIC PIXEL-BASED WEIGHTING FACTOR DUAL-ENERGY X-RAY IMAGING SYSTEM

open access: yes, 2018
This thesis investigates the development and implementation of a novel patient specific pixel-based weighting factor algorithm for dual-energy x-ray imaging. The first chapter of this thesis is an introduction on the components of an x-ray imaging system,
Reno, Michael
core  

Dynamical generation of neutrino mass scales

open access: yesPhysics Letters B, 2019
In this letter we present a simple scenario where the mass scales associated to atmospheric and solar neutrino oscillations are obtained through the dynamical generation of neutrino masses. The main idea is that the two different scales are the result of
Alfredo Aranda   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Dual-energy Stereoscopic X-ray Imaging to Enhance Soft-tissue Contrast in Lung Imaging

open access: yes, 2016
In this thesis, dual-energy x-ray technique is developed and discussed for a stereoscopic imaging system to enhance soft tissue contrast in lung imaging.
Bowman, Wesley
core  

Assessment of tibial fracture healing with dual energy X-ray absorptiometry: influence of metallic implants at the fracture site [PDF]

open access: yes, 1995
Evaluation of the progress of fracture healing traditionally combines manual fracture manipulation with a visual radiographic assessment. This approach can lead to satisfactory healing, but trouble can ensue when the type of fixation compromises the ...
Cattermole, Howard Charles
core  

Iodine Extravasation Quantification on Dual-Energy CT of the Brain Performed after Mechanical Thrombectomy for Acute Ischemic Stroke Can Predict Hemorrhagic Complications

open access: yesAmerican Journal of Neuroradiology, 2018
Eighty-five consecutive patients who underwent brain dual-energy CT immediately after mechanical thrombectomy for acute ischemic stroke between August 2013 and January 2017 were included. Two radiologists independently evaluated dual-energy CT images for
M. Bonatti   +7 more
semanticscholar   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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