Results 71 to 80 of about 488,497 (353)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Objective: To investigate the application value of dual-energy scanning scheme in neck-chest-abdomen-pelvis combined enhanced CT in patients with breast cancer patients by comparing with the conventional scanning scheme. Methods: A retrospective analysis
Hong WANG +6 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Advances of dual source, dual-energy imaging in postmortem CT
This paper focuses on the use of multi-detector row dual-energy computed tomography (DECT) in the evaluation of postmortal examinations. The use of dual energy moves postmortem CT to an entirely new dimension of diagnostic sensitivity where contrast in ...
Jackowski, Christian +3 more
core +1 more source
Dual-Energy CT: New Horizon in Medical Imaging
Dual-energy CT has remained underutilized over the past decade probably due to a cumbersome workflow issue and current technical limitations. Clinical radiologists should be made aware of the potential clinical benefits of dual-energy CT over single ...
H. Goo, J. Goo
semanticscholar +1 more source
Energy Efficient Dual Issue Embedded Processor [PDF]
While energy efficiency is essential to extend the battery life of embedded devices, performance cannot be ignored. Highperformance superscalar embedded processors are more energy efficient than low performance scalar processors, however,they consume ...
Hanni Lozano, Mabo Ito
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Investigating Patients with Pulmonary Hypertension Under Detector-Based Spectral Computed Tomography
Background: Pulmonary hypertension (PH) is characterized by elevated pressure in the pulmonary artery. Currently, most dual-energy CT (DECT) research focuses on the application of iodine mapping in pulmonary embolism. However, little attention is paid to
Hsien-Fu Cheng +2 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Dual energy subtraction: principles and clinical applications
Two technical solutions using single or dual shot offer different advantages and disadvantages for dual energy subtraction. The principles of these are explained and the main clinical applications with results are demonstrated.
Szucs-Farkas, Zsolt, Vock, Peter
core +1 more source

