Results 31 to 40 of about 161,013 (263)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Performance-Based Plastic Design of Moment Frame-Steel Plate Shear Wall as a Dual System [PDF]

Civil Engineering Infrastructures Journal, 2017
Steel Plate Shear Wall (SPSW) is an emerging seismic load-resistant system that, compared to other systems, enjoys the advantages of stable ductile behavior, fewer detailing requirements, rapid constructability, and economy.
Gholamreza Abdollahzadeh, Hamed kuchakzadeh, Alireza Mirzagoltabar   +2 more
doaj   +1 more source

Design of LTE/Sub-6 GHz Dual-Band Transparent Antenna Using Frame-Structured Metal Mesh Conductive Film

Nanomaterials, 2023
This paper proposes a dual-band transparent antenna using frame-structured metal mesh conductive film (MMCF). The frame-structured metal mesh conductive film is based on the conductive-coated thin film and forms a narrow strip surrounding the edge of the
Yu-Ming Lin, Hung-Wei Wu, Shoou-Jinn Chang   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

$p$-adic Dual Shearlet Frames [PDF]

Sahand Communications in Mathematical Analysis, 2019
We introduced the continuous and discrete $p$-adic shearlet systems. We restrict ourselves to a brief description of the $p$-adic theory and shearlets in real case.
Mahdieh Fatemidokht, Ataollah Askari Hemmat   +1 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Bending Fields for Dual Curves

Axioms
This paper provides several new characterizations of the infinitesimal bending of dual curves, which is defined as an infinitesimal deformation preserving dual arc length (with appropriate precision).
Marija S. Najdanović, Svetozar R. Rančić, Ljubica S. Velimirović   +2 more
doaj   +1 more source

Supervised dual tight frame learning with deep thresholding network for phase retrieval

IET Image Processing, 2022
Data‐driven tight frames are popular for solving imaging inverse problems. However, the imaging quality is limited by the representation ability of single tight frame and thresholds tuned manually.
Baoshun Shi, Qiusheng Lian, Yueming Su
doaj   +1 more source