Results 161 to 170 of about 38,591 (266)

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

The impact of scavenging air state on the combustion and emission performance of marine two-stroke dual-fuel engine. [PDF]

Sci Rep
Yu H, Gao J, Zhang P, Han FJ, Yang Q, Cui B.   +5 more
europepmc   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Optimization of PID control parameters for marine dual-fuel engine using improved particle swarm algorithm. [PDF]

Sci Rep
Hu Z, Guo W, Zhou K, Wang L, Wang F, Yuan J.   +5 more
europepmc   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Comparative assessment of emissions, performance, and economics parameters for a dual-fuel diesel generator operating with rice bran biodiesel and hydrogen. [PDF]

Heliyon
Laguado-Ramírez R, Hernandez-Villamizar F, Duarte-Forero J.   +2 more
europepmc   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Dual-Fuel Propelled Nanomotors with Two-Stage Permeation for Deep Bacterial Infection in the Treatment of Pulpitis. [PDF]

Adv Sci (Weinh)
Wang H, Chen X, Zhang L, Han Z, Zheng J, Qi Y, Zhao W, Xu X, Li T, Zhou Y, Bao P, Xue X.   +11 more
europepmc   +1 more source

Frustrated Lewis Pairs and Metallic Ni Synergistically Enabled Low‐Temperature Hydrogenolysis of Lignin Models

Advanced Science, EarlyView.
Nickel–aluminum composite oxide (NiAlOx‐300) derived from NiAl layered double hydroxide showed high activity for hydrogenolysis of various lignin models. Especially, hydrogenolysis of benzyl phenyl ether could be efficiently proceeded at 20°C and 1 MPa H2.
Jinpeng Liang, Ziyi Ma, Zhaoxi Cai, Kongqian Liang, Chenglei Xiao, Sitong Chen, Na Wang, Zhimin Xue, Chao Xie, Jinliang Song   +9 more
wiley   +1 more source

Impact of pilot diesel injection timing on performance and emission characteristics of marine natural gas/diesel dual-fuel engine. [PDF]

Sci Rep
Zhang X, Gao J, Fan D, Yang Q, Han F, Yu H.   +5 more
europepmc   +1 more source