Results 51 to 60 of about 8,734,078 (281)

A Hybrid Neuromorphic Framework With Dual-Mode Memory and Adaptive Synaptic Plasticity

open access: yesIEEE Access
By simulating neural parallelism, event-driven computation, and adaptive learning, neuromorphic computing provides a revolutionary departure from conventional Von Neumann architectures.
Emir Husain, Padma Jayaraman
doaj   +1 more source

Short- and Long-term Memory: A Complementary Dual-network Memory Model

open access: yes, 2016
In recent years, the possible applications of artificial intelligence (AI) and deep learning have increased drastically. However, the algorithms which constitute the learning mechanisms in deep learning are based largely on the same principles as when formalised about half a century ago.
openaire   +2 more sources

DO YOU REMEMBER THE WORDS? DUAL-CODING METHOD ON LONG-TERM MEMORY

open access: yesJurnal Psikologi, 2020
For students, long-term memory is required for individuals to study at various levels of education. An effective method is needed to help student to remember. This study aims to determine the dual-coding method on long-term memory in two levels of education: primary school and university.
openaire   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Mnemis: Dual-Route Retrieval on Hierarchical Graphs for Long-Term LLM Memory

open access: yesProceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)
Accepted to ...
Zihao Tang   +11 more
openaire   +3 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Research on Engineering Applications of Pipeline Stress Internal Detection Based on the Dual Excitation Magnetic Field

open access: yesShiyou jixie, 2023
Multiple methods,such as ultrasonic,radiographic and magnetic memory methods,can be used to measure the pipeline surface stress,and yet these methods are found with no application to pipeline online stress internal detection.Based on the structure of an ...
Tian Ye   +4 more
doaj  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

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