Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Feasibility study of hydrogen-ammonia synergistic combustion in scramjets across broad Mach ranges. [PDF]
Song X +6 more
europepmc +1 more source
Navier Stokes in Higher Order Dual Numbers and Other Algebraic Systems
Mohammed Farhaan
openalex +1 more source
Fully Parameterized Reduced Order Models Using Hyper-Dual Numbers and Component Mode Synthesis
M. Bonney, D. Kammer, M. Brake
semanticscholar +1 more source
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
A comprehensive study on the dual species biofilm formation of clinical <i>Staphylococcus aureus</i> and <i>Candida albicans</i> strains from the same origins. [PDF]
Li Y +13 more
europepmc +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Subnuclear organization and mislocalization of plasmids reduce transgene expression. [PDF]
Gu N +4 more
europepmc +1 more source
On Dual-Hyperbolic Numbers with Generalized Fibonacci and Lucas Numbers Components
Mehmet Ali̇ Güngör, Arzu CİHAN
openalex +2 more sources

