Results 211 to 220 of about 369,263 (302)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Establishment and application of a dual chip digital PCR assay for detection of PDCoV and PEDV. [PDF]

Front Vet Sci
Zhang Y, Dong F, Zhang Y, Feng Y, Hu J, Li Y, Xia L, Zu S, Lu H, Wei Z.   +9 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Research on Kinematic Calibration and Trajectory Tracking of the Dual-Robot Collaborative Grinding and Polishing System. [PDF]

Sensors (Basel)
Yan W, Xu L, Sun Y, Xu H, Ji Z.
europepmc   +1 more source

A self-dual poset on objects counted by the Catalan numbers and a type-B analogue

, 1999
Miklós Bóna, Rodica Simion
openalex   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Dual-Toxin-Producing <i>Clostridium botulinum</i> Strain Isolated from a Foodborne Botulism Case in Korea: Genomic and Functional Insights. [PDF]

Toxins (Basel)
Choi ES, Choi CH, Jeon JH, Kim SH, Song HJ, Yi H, Rhie GE, Chung YS.   +7 more
europepmc   +1 more source

On the computation of stabilized tensor functors and the relative algebraic 𝐾-theory of dual numbers

, 2001
Randy McCarthy
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

A specific gene expression program underlies antigen archiving by lymphatic endothelial cells in mammalian lymph nodes. [PDF]

Nat Commun
Sheridan RM, Doan TA, Lucas CJ, Forward TS, Fleming I, Olsen VM, Qvale AM, Davenport BJ, Zarrella K, Harbell MG, Uecker-Martin A, Morrison TE, Hesselberth JR, Tamburini BAJ.   +13 more
europepmc   +1 more source