Results 111 to 120 of about 41,512 (287)
Advanced Science, EarlyView.The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen +15 more
wiley +1 more source
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Advanced Science, EarlyView.Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source
A Dual Reciprocity Boundary Element Method for the Regularized Numerical Solution of the Inverse Source Problem Associated to the Poisson Equation [PDF]
, 2003 Adrian Farcas +4 more
openalex +1 more source
The dual reciprocity boundary element method solution of fluid flow problems
, 2020 Bu tezde, viskoz ve sıkıştırılamayan akışkanların iki boyutlu,zamana bağlı, katmanlı akımları karşılıklı sınır elemanları yöntemiile çözülmüştür. Enerji denkleminin eklenmesiyle doğal ve karışıkkonveksiyon akımları da çözülmüştür. Nano ve mikropolar akışkanlarınkapalı /mbox{bölgelerdeki} doğal konveksiyon akımlarının çözümüoldukça yüksek Rayleigh ...
openaire +1 more source
Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects
Advanced Science, EarlyView.Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang +9 more
wiley +1 more source
Two-Dimensional Incompressible Viscous Flow Simulation Using Velocity-Vorticity Dual Reciprocity Boundary Element Method [PDF]
, 2004 T. I. Eldho, D.L. Young
openalex +1 more source
Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine
Advanced Science, EarlyView.This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng +18 more
wiley +1 more source