Results 61 to 70 of about 352,668 (312)
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A note on the minimum‐norm in dual space approach to some classical linear optimal control problems
Some classical optimal control problems of linear systems can be characterized as finding minimum‐norm vectors from within linear varieties in appropriate dual spaces.
Yue Zhou, Pushkin Kachroo, Kaan Ozbay
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
New Matrix Domains Arising from the Euler Totient Function and Its Summatory Function
The matrix formed using the Euler totient function together with its summatory function is employed to generate new sequence spaces. After establishing several features of these spaces, their duals are explicitly identified.
Merve Ilkhan Kara
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Slant helices, Darboux helices and similar curves in dual space D3 [PDF]
In this paper, we give definitions and characterizations of slant helices, normalized Darboux helices and similar curves in dual space D3. First, we define dual slant helices and dual normalized Darboux helices and show that dual slant helices are also ...
Sahiner Burak, Önder Mehmet
doaj
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The celestial chiral algebra of self-dual gravity on Eguchi-Hanson space
We consider the twistor description of classical self-dual Einstein gravity in the presence of a defect operator wrapping a certain ℂℙ1. The backreaction of this defect deforms the flat twistor space to that of Eguchi-Hanson space.
Roland Bittleston +2 more
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Financial Decisions Based on Zero-Sum Games: New Conceptual and Mathematical Outcomes
All the n possible returns on a financial asset are the components of an element of a linear space over R. This paper shows how to transfer all these n possible returns on a one-dimensional straight line.
Pierpaolo Angelini
doaj +1 more source

