Results 91 to 100 of about 10,808 (265)

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Non-invertible SO(2) symmetry of 4d Maxwell from continuous gaugings

Journal of High Energy Physics
We describe the self-duality symmetries for 4d Maxwell theory at any value of the coupling τ via topological manipulations that include gauging continuous symmetries with flat connections. Moreover, we demonstrate that the SL(2, ℤ) duality of Maxwell can
Elise Paznokas
doaj   +1 more source

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source

Multi-cell downlink coordinated beam forming algorithm based on fairness duality theory

Tongxin xuebao, 2013
With the goal to optimize the multi-cell downlink beamforming based on the criterion of the worst-user rate maximization,the Lagrangian duality theory was first used to derive a virtual multi-cell uplink optimization problem that was dual to the primal ...
Shi-wen HE, Yong-ming HUANG, Lv-xi YANG
doaj  

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

The Mean and the Variance as Dual Concepts in a Fundamental Duality

Axioms
A basic duality arises throughout the mathematical and natural sciences. Traditionally, logic is thought to be based on the Boolean logic of subsets, but the development of category theory in the mid-twentieth century shows the duality between subsets ...
David Ellerman
doaj   +1 more source

The General Review of Dualities Theory in Managing Organizational Change [PDF]

International Journal of Management, Accounting and Economics, 2015
This article is about how duality theory is perceived by leaders and how we should focus on its element. It is important because organization tend to underestimate the importance of dualities. This research will show that duality thinking provides us the
Wong Whye, Rashad Yazdanifard
doaj  

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

T-duality and flavor symmetries in Little String Theories

Journal of High Energy Physics
We explore the T-duality web of 6D Heterotic Little String Theories, focusing on flavor algebra reducing deformations. A careful analysis of the full flavor algebra, including Abelian factors, shows that the flavor rank is preserved under T-duality. This
Hamza Ahmed, Paul-Konstantin Oehlmann, Fabian Ruehle   +2 more
doaj   +1 more source

A perfectoid duality between M-theory and F-theory

Nuclear Physics B
We present a non-singular, definition-level formulation of F-theory by replacing the traditional shrinking-fiber limit of M-theory with compactification on a tower-completed circle described using perfectoid geometry and condensed mathematics.
Arshid Shabir, Bobby Eka Gunara, Mir Faizal   +2 more
doaj   +1 more source