Results 41 to 50 of about 7,143,501 (298)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Multi-cell downlink coordinated beam forming algorithm based on fairness duality theory
Tongxin xuebao, 2013 With the goal to optimize the multi-cell downlink beamforming based on the criterion of the worst-user rate maximization,the Lagrangian duality theory was first used to derive a virtual multi-cell uplink optimization problem that was dual to the primal ...
Shi-wen HE, Yong-ming HUANG, Lv-xi YANG
doaj +2 more sources
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Linear programming with inequality constraints via entropic perturbation
International Journal of Mathematics and Mathematical Sciences, 1996 A dual convex programming approach to solving linear programs with inequality constraints through entropic perturbation is derived. The amount of perturbation required depends on the desired accuracy of the optimum.
H.-S. Jacob Tsao, Shu-Cherng Fang
doaj +1 more source
Frequency aware robust economic dispatch
Journal of Modern Power Systems and Clean Energy, 2016 This paper proposes a novel frequency aware robust economic dispatch (FARED) approach to exploit the synergistic capability of accommodating uncertain loads and renewable generation by accounting for both the frequency regulation effect and optimal ...
Donglei Sun +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Cogent EngineeringThe progression of industrial revolutions has redefined robots, moving them from isolated motions in structured settings to adaptive force-aware interactions in human environments. This evolution reveals a central pivot, both philosophical and technical:
Xiaohui Zhu, Zhigang Zhang, Fanzi Meng
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Complete Solutions to General Box-Constrained Global Optimization Problems
Journal of Applied Mathematics, 2011 This paper presents a global optimization method for solving general nonlinear programming problems subjected to box constraints. Regardless of convexity or nonconvexity, by introducing a differential flow on the dual feasible space, a set of complete ...
Dan Wu, Youlin Shang
doaj +1 more source
N-K Constrained Composite Generation and Transmission Expansion Planning With Interval Load
IEEE Access, 2017 The uncertainties of the predicted load demand and N-K contingencies are very significant aspects to composite generation and transmission expansion planning (CGTEP).
Shaoyun Hong +2 more
doaj +1 more source