Results 191 to 200 of about 114,439 (345)

Fast Myosin Binding Protein‐C Is a Vital Regulator in Young and Aged Fast Skeletal Muscle Homeostasis

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Skeletal muscle plays a vital role in voluntary movement and locomotion. Fast‐twitch muscle fibres are characterized by their rapid contraction kinetics, high‐force generation and a distinct gene expression profile compared to slow‐twitch fibres.
Akhil Baby, Kalyani Ananthamohan, Brenna N. McIntyre, Sankar Natesan, Taejeong Song   +4 more
wiley   +1 more source

Role of Peptides in Skeletal Muscle Wasting: A Scoping Review

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Systemic muscle wasting is a prevalent condition that predicts adverse health outcomes in aging and disease. Despite its clinical relevance, the development of predictive biomarkers and effective pharmacological therapies remains limited. Peptides have recently gained attention for their diverse bioactive functions, positioning them
Petar Naumovski, Bart De Spiegeleer, Aster Wakjira, Christophe Van De Wiele, Vincent Mouly, Katarzyna Goljanek‐Whysall, Kauê Santana da Costa, Ewerton Cristhian Lima de Oliveira, Evelien Wynendaele, Anton De Spiegeleer   +9 more
wiley   +1 more source

An Isogenic Human Myoblast Cell Model for Cystinosis Myopathy Reveals Alteration of Key Myogenic Regulatory Proteins

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Cystinosis is a rare multisystem, autosomal recessive disease caused by dysfunction or loss of cystinosin (CTNS), which results in lysosomal cystine accumulation, primarily affecting the kidneys. Advances in renal transplantation, cysteamine treatment and improved medical care have increased life expectancy, revealing additional ...
Louise Medaer, Roger Mora, Zhuoheng Zhou, Nefele Giarratana, Laura Yedigaryan, Rita La Rovere, Elena Levtchenko, Vincent Mouly, Els Verhoeyen, Sebastiaan Eeltink, Achim Treumann, Tim Vervliet, Maurilio Sampaolesi, Rik Gijsbers   +13 more
wiley   +1 more source

534. Cell Therapeutic Approach to Duchenne Muscular Dystrophy Using Myogenic Differentiation of Multipotent Mesenchymal Stromal Cells [PDF]

, 2009

openalex   +1 more source

P-226 One stop duchenne muscular dystrophy clinic; a unique NHS – young adult hospice collaboration [PDF]

, 2021
A.G. Brain, Carol Ransome
openalex   +1 more source

Leptin From Fibro‐Adipogenic Progenitor Cells (FAPs) Regulates Masseter Muscle Disuse Atrophy and Ectopic Fat Accumulation

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Excessive fat accumulation in muscles with disuse atrophy may impair muscle physiologic function and exacerbate the progression of atrophy, with causes largely unexplored. Evidence indicates leptin plays a crucial role in regulating skeletal muscle fat metabolism.
Song Xinyi, Li Tingting, Liu Xiaoyu, Yan Hao, Li Qingchun, Liu Wei, Cheng Yuhe, Zhang Keke, Chen Yi, Gao Ang, Hong Yongfeng, Wang Yuanyin, Wu Tingting   +12 more
wiley   +1 more source

Cardiopulmonary exercise testing as an integrative approach to explore physiological limitations in Duchenne muscular dystrophy [PDF]

Meghana Bomma, Donovan J. Lott, Sean C. Forbes, Renata Shih, John‐Anthony Coppola, Jeffrey W. Christle, Tina Duong, Joseph F. Russo, A. Pant, Carmen Leon‐Astudillo, Julie Berthy, Claire Cousins, Manuela Corti, Barry J. Byrne, James R. May, Wei Xue, Tanja Taivassalo   +16 more
openalex   +1 more source

C2C12‐Derived ApoVs Promote Skeletal Muscle Development and Ameliorate Age‐Related Muscle Loss Through Igf1r/PI3K/AKT/mTOR Pathway

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Apoptosis coincides with the differentiation of skeletal myoblasts, and numerous studies have shown that the apoptotic activity is required for myogenic differentiation. Although the role of apoptosis in skeletal muscle differentiation has been well documented, its mechanism is largely unknown.
Aiwen Jiang, Yi Liu, Luyao Wang, Haifei Wang, Shenglong Wu, Wenbin Bao   +5 more
wiley   +1 more source

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

Science, 2016
Christopher E. Nelson, Chady H. Hakim, David G. Ousterout, P. Thakore, E. A. Moreb, R. Rivera, S. Madhavan, Xiufang Pan, F. Ran, Winston X. Yan, A. Asokan, Feng Zhang, D. Duan, C. Gersbach   +13 more
semanticscholar   +1 more source

Illuminating Satellite Cells: Light Sheet Fluorescence Microscopy for 3D Imaging of Murine Skeletal Muscles Damaged by Ex Vivo Forced Eccentric Contraction

Microscopy Research and Technique, Volume 88, Issue 12, Page 3339-3347, December 2025.
This study presents the light sheet fluorescence microscopy (LSFM) as a tool for 3D‐imaging of whole skeletal muscle to reveal satellite cells (SCs), the muscle stem cells that activate following damage to repair injured tissue. After tissue clearing and whole‐mount staining process aimed to enable optical access and specific cell labeling (1), murine ...
Rachele Garella, Elisa Imbimbo, Francesco Palmieri, Alessia Tani, Martina Parigi, Flaminia Chellini, Alessandra La Contana, Monica Mattioli Belmonte, Aurora Longhin, Ludovico Silvestri, Chiara Sassoli, Roberta Squecco   +11 more
wiley   +1 more source