Results 91 to 100 of about 235,784 (190)

An investigation into the effects of dystrophin on the lateral mobility of muscle membrane components. [PDF]

, 1999
Dystrophin is the product of the Duchenne Muscular Dystrophy gene locus, whose absence results in progressive skeletal muscle breakdown. Despite considerable work on the localisation of dystrophin and its associated complex, its role in muscle function ...
Dutton, A.L., Dutton, Anna Louise
core  

Sociodemographic and Clinical Profile of Adult Males With Duchenne Muscular Dystrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Due to improvements in clinical care, individuals with Duchenne muscular dystrophy (DMD) are living into adulthood, but little has been published about adults with DMD. We describe key characteristics of adults with DMD using US population‐based surveillance data.
Manju Jayasimha Pula Jayaram, Hollie A. Clark, Natalie Street, Yining Yang, Shannon Kilburn, Shiny Thomas, Christina Westfield, Katherine D. Mathews, Emma Ciafaloni, Aida Soim, Muscular Dystrophy Surveillance, Tracking, and Research Network (MD STARnet)   +12 more
wiley   +1 more source

Echocardiographic examinations of Duchenne muscular dystrophy

, 2018
Follow-up data of echocardiographic examinations of Japanese Duchenne muscular dystrophy ...
Yamamoto, Tetsushi, Tetsushi Yamamoto (5024189), Masafumi Matsuo (4637134), Matsuo, Masafumi   +3 more
core   +1 more source

Systematic Review of Patient‐ and Observer‐Reported Outcomes of Fatigue in Pediatric Neuromuscular Disorders

Muscle &Nerve, EarlyView.
ABSTRACT Fatigue is a burdensome symptom for pediatric populations with neuromuscular disorders, often assessed using patient‐ and observer‐reported outcomes. The three aims of this systematic review are to: (1) explore, summarize and critically appraise primary studies that measure fatigue in pediatric neuromuscular disorders using patient‐ and ...
Monica Marzouk, Kayla M. D. Cornett, Gabrielle A. Donlevy, Carl Young, Joshua Burns, Manoj P. Menezes, Marnee J. McKay   +6 more
wiley   +1 more source

The value of dog for knowledge of human Duchenne muscular dystrophy: New findings in pathogenesis and therapeutic advances

, 2015
Duchenne muscular dystrophy (DMD) is the most devastating form of inherited muscular dystrophy in men. The loss of dystrophin causes progressive weakness and degeneration of skeletal and cardiac muscle leading to the replacement of muscle by connective ...
Malvestio, Lygia M. [UNESP], de Moraes, Flávio Ruas [UNESP], de Moraes, Julieta R. Engrácia [UNESP], Martins, Isabela M. [UNESP]   +3 more
core   +1 more source

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.

PLoS ONE, 2016
Duchenne muscular dystrophy is a severe and currently incurable progressive neuromuscular condition, caused by mutations in the DMD gene that result in the inability to produce dystrophin. Lack of dystrophin leads to loss of muscle fibres and a reduction
Narinder Janghra, Jennifer E Morgan, Caroline A Sewry, Francis X Wilson, Kay E Davies, Francesco Muntoni, Jonathon Tinsley   +6 more
doaj   +1 more source

A Roadmap to Newborn Screening for Duchenne Muscular Dystrophy

International Journal of Neonatal Screening, 2017
Duchenne muscular dystrophy (DMD) is the most common childhood form of muscular dystrophy, with an estimated frequency of 1:5000 live births. The impact of the disease presents as early as infancy with significant developmental delays, and ultimately ...
Samiah A. Al-Zaidy, Michele Lloyd-Puryear, Annie Kennedy, Veronica Lopez, Jerry R. Mendell   +4 more
doaj   +1 more source

Beyond conventional anthropometry: Muscle‐related indicators and muscle strength in adults with congenital heart disease: A retrospective study with a comparison group

Nutrition in Clinical Practice, EarlyView.
Abstract Anthropometric characteristics and muscle strength remain insufficiently characterized in adults with congenital heart disease (CHD). The aim of the study was to characterize anthropometric indicators and muscle strength in hospitalized adults with CHD and examine differences according to cardiac lesion complexity. Exploratory comparisons with
Hyan Ribeiro Prudêncio de Sousa, Cláudia Porto Sabino Pinho   +1 more
wiley   +1 more source

Studies on muscular dystrophy associated genes [PDF]

, 2007
Muscular dystrophy is a collective group of genetic disorder that results in progressive wasting of skeletal muscle. Dysferlin, the gene responsible for Limb Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM) was found to be a member of
Bakir, Hadil
core  

Therapeutics in Duchenne muscular dystrophy [PDF]

NeuroRX, 2006
Duchenne muscular dystrophy (DMD) is a fatal disorder affecting approximately 1 in 3,500 live born males, characterized by progressive muscle weakness. Several different strategies are being investigated in developing a cure for this disorder. Until a cure is found, therapeutic and supportive care is essential in preventing complications and improving ...
openaire   +2 more sources