Results 161 to 170 of about 702,469 (311)

Influence of bulk turbulence and entrance boundary layer thickness on the curved duct flow field [PDF]

open access: yes
The objective of this investigation was the experimental evaluation of bulk turbulence and boundary thickness influence on the secondary flow development in a square, 90 deg turning duct.
Crawford, Roger A., Peters, Carroll E.
core   +1 more source

Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine‐dependent Tumor Subset Under Metabolic Relationships With CAFs.

open access: yesAdvanced Science, EarlyView.
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin   +25 more
wiley   +1 more source

Effects of Pancreatic Duct Stenting on Nutrition and Pancreatic Function in Unresectable Pancreatic Cancer: A Pilot Study. [PDF]

open access: yesJGH Open
Watsuji K   +12 more
europepmc   +1 more source

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

open access: yesAdvanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He   +8 more
wiley   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

open access: yesAdvanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu   +6 more
wiley   +1 more source

Flight-measured inlet pressure transients accompanying engine compressor surges on the F-111A airplane [PDF]

open access: yes
Two-F-111A airplanes were subjected to conditions that caused engine compressor surges and accompanying duct hammershock pressure transients. Flight speed ranged from Mach 0.71 to Mach 2.23, and altitude varied from approximately 3200 meters to 14,500 ...
Holzman, J. K., Nugent, J.
core   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

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