Results 31 to 40 of about 702,469 (311)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A Classifying-Inversion Method of Offshore Atmospheric Duct Parameters Using AIS Data Based on Artificial Intelligence

open access: yesRemote Sensing, 2022
Atmospheric duct parameters inversion is an important aspect of microwave-band radar and communication system performance evaluation. AIS (Automatic Identification System) is one of the signal sources used for atmospheric duct parameters inversion ...
Jie Han   +7 more
doaj   +1 more source

An optimisation approach to the location and sizing of multiple leaks in a duct [PDF]

open access: yes, 2006
A single leak in a duct can be located, and its size predicted, by measuring the input impedance of the duct and then solving an inverse problem. However, extending this procedure to a duct containing several leaks is non-trivial, with the resulting ...
Chilekwa, V., Sharp, D.
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Ground Test and Numerical Simulation on Ground Effect of Ducted Propeller System

open access: yesXibei Gongye Daxue Xuebao, 2020
The aerodynamic performances of a ducted propeller system applied in a manned vertical takeoff and landing aircraft considering the ground effect are investigated.

doaj   +1 more source

Apparatus for supplying conditioned air at a substantially constant temperature and humidity [PDF]

open access: yes, 1980
The apparatus includes a supply duct coupled to a source of supply air for carrying the supply air therethrough. A return duct is coupled to the supply duct for carrying return conditioned air therethrough. A temperature reducing device is coupled to the
Obler, H. D.
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Salivary duct carcinoma [PDF]

open access: yesCancer, 1993
Salivary duct carcinoma (SDC) is a distinctive salivary gland neoplasm morphologically characterized by intraductal and infiltrating components. Most tumors occur in the major salivary glands and demonstrate a propensity for invasive growth with early regional and distant metastases.
R, Delgado   +2 more
openaire   +2 more sources

Fabrication process of a high temperature polymer matrix engine duct [PDF]

open access: yes, 1985
The process that was used in the molding of an advanced composite outer by-pass duct planned for the F404 engine is discussed. This duct was developed as a potential replacement for the existing titanium duct in order to reduce both the weight and cost ...
Pratt, R. D., Wilson, A. J.
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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