Results 161 to 170 of about 776,755 (348)

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

Retrograde Double-Balloon Enteroscopy Endoscopic Retrograde Pancreatography With Interventional Radiology Rendezvous of a Transplanted Pancreas. [PDF]

ACG Case Rep J
Bayudan A, Wang M, Kolli P, Larsen M.
europepmc   +1 more source

KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression

Advanced Science, EarlyView.
Cholangiocarcinoma (CCA) driven by oncogenic KRAS depends on its continuous activation for tumor maintenance. Using a conditional KRAS model, the authors show that turning off KRAS triggers rapid tumor regression accompanied by immune cell infiltration and cytokine release. The findings uncover a KRAS–senescence–immune signaling axis and highlight KRAS
Youwei Qiao, Matthew F. Yee, Chaitanya N. Parikh, Boyang Ma, Yueying Cao, Yu‐Huan Shih, Joae Qiong Wu, Marcus Ruscetti, Shun‐Qing Liang, Wen Xue   +9 more
wiley   +1 more source

Low‑dose indocyanine green fluorescence cholangiography in laparoscopic cholecystectomy: visualization performance across validated risk scores. [PDF]

Langenbecks Arch Surg
Pujol-Cano N, Morón-Canis JM, Palma-Zamora E, Bonnin-Pascual J, Coll-Sastre M, González-Argenté FX, Molina-Romero FX.   +6 more
europepmc   +1 more source

Cubical Anatomy of Several Ducts and Vessels by Injection Method of Acrylic Resin XI. Arterial distribution of the palatine tonsil in some mammals

, 1961
Isamu Azuma
openalex   +2 more sources

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Hepatectomy inside the Portal Ring in a Patient with Absence of Portal Vein Bifurcation: A Case Report. [PDF]

Surg Case Rep
Takagi A, Takahashi D, Maeda A, Takayama Y, Takahashi T, Aoyama H, Hosoi T.   +6 more
europepmc   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Anatomical Trickery in Acute Cholecystitis: Very Low Cystic Duct Insertion Near the Ampulla of Vater. [PDF]

Cureus
Kim K, Conway D, Noches-Garcia A.
europepmc   +1 more source

Surgical Anatomy of Nasolacrimal Duct and Sac in Human Cadavers

, 2014
Tulika Gupta, Suhalika S Sahni, Ruchi Goyal   +2 more
openalex   +1 more source