Results 121 to 130 of about 168,901 (301)
Advanced Science, EarlyView.As a downstream target of α2δ1‐mediated calcium signaling, SIRT4 serves as an oncogene to promote the stemness of pancreatic cancer via deacetylating ENO1 directly at K358, leading to attenuated ENO1's RNA‐binding capacity, enhanced glycolytic substrate 2‐PG binding and robust glycolytic activity to increase the level of lactate that induce histone ...
Mengzhu Lv +10 more
wiley +1 more source
대한영상의학회지, 2018 Metaplastic breast carcinoma is a rare type of neoplasms with mixed epithelial and mesenchymal differentiation. Metaplastic carcinoma with chondroid differentiation is relatively an uncommon type among the different types of metaplastic carcinoma.
Leehi Joo, Soo Hyun Yeo, Sun Young Kwon
doaj +1 more source
INVESTIGATING INVASION IN DUCTAL CARCINOMA IN SITU WITH TOPOGRAPHICAL SINGLE CELL GENOME SEQUENCING [PDF]
, 2018 Synchronous Ductal Carcinoma in situ (DCIS-IDC) is an early stage breast cancer invasion in which it is possible to delineate genomic evolution during invasion because of the presence of both in situ and invasive regions within the same sample.
Casasent, Anna, Casasent, Anna
core +1 more source
Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes. [PDF]
, 2003 A considerable body of research indicates that mammary gland branching morphogenesis is dependent, in part, on the extracellular matrix (ECM), ECM-receptors, such as integrins and other ECM receptors, and ECM-degrading enzymes, including matrix ...
A Amour +139 more
core +2 more sources
Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications
Advanced Science, EarlyView.HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang +5 more
wiley +1 more source
Кубанский научный медицинский вестникBackground. Angiogenesis plays a crucial role in the progression of breast cancer. Identifying and investigating the key components of this process, focused on phenotype as well as microenvironment of the tumor, is considered highly relevant for ...
K. A. Aliyev +3 more
doaj +1 more source
BMC Research Notes, 2018 Objectives The aim of this study was to determine the frequency of metaplastic breast carcinoma and invasive micropapillary carcinoma in our population and also to compare the clinico-pathologic features of metaplastic breast carcinoma and invasive ...
Atif Ali Hashmi +10 more
doaj +1 more source
Advanced Science, EarlyView.LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li +8 more
wiley +1 more source
Deep learning analysis of breast MRIs for prediction of occult invasive disease in ductal carcinoma in situ [PDF]
arXiv, 2017 Purpose: To determine whether deep learning-based algorithms applied to breast MR images can aid in the prediction of occult invasive disease following the di- agnosis of ductal carcinoma in situ (DCIS) by core needle biopsy. Material and Methods: In this institutional review board-approved study, we analyzed dynamic contrast-enhanced fat-saturated T1 ...
arxiv
Case Report: Ductal Carcinoma in Situ Within A Granulomatous Mastitis
European Journal of Breast Health, 2018 Granulomatous lobular mastitis is a rare chronic breast disease, firstly described by Kessler and Wolloch in 1972. In this article we present a 35-yearold patient with granulomatous lobular mastitis and in situ ductal carcinoma and discuss ...
Mine Özşen +2 more
doaj +1 more source