Results 141 to 150 of about 1,818,460 (375)

Paracrine Orchestration of Tumor Microenvironment Remodeling Induced by GLO1 Potentiates Lymph Node Metastasis in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing of lymph node (LN) samples is performed, and a comprehensive landscape of the entire ecosystem is generated. Paracrine orchestration of TME remodeling induced by GLO1 potentiates LN metastasis in breast cancer. This study offers novel perspectives on the microenvironment remodeling of breast cancer LN metastases, suggesting ...
Jindong Xie   +16 more
wiley   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

open access: yesHepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou   +15 more
wiley   +1 more source

Deep learning-based risk stratification of ductal carcinoma in situ using mammography and abbreviated breast magnetic resonance imaging

open access: yesFrontiers in Oncology
BackgroundCurrent management of ductal carcinoma in situ lacks robust risk stratification tools, leading to universal surgical and radiotherapy interventions despite heterogeneous progression risks. Optimizing therapeutic balance remains a critical unmet
Tingfeng Zhang   +5 more
doaj   +1 more source

Secretory Breast Carcinoma: A Case Report with MRI Findings

open access: yes대한영상의학회지, 2019
Secretory carcinoma of the breast is an extremely rare, clinically and histologically distinct variant of invasive ductal carcinoma, with an indolent growth pattern and a more favorable prognosis than that of typical ductal carcinoma.
Sung Hee Shin   +6 more
doaj   +1 more source

Plasma DNMT1 Activity for Assessing Tumor Burden and Predicting Neoadjuvant Therapy Response in Breast Cancer

open access: yesAdvanced Science, EarlyView.
In this work, a detection method is presented for the activity of plasma DNA methyltransferase 1 (DNMT1), namely DNMT1 Identification by Variable Activity (DIVA). DIVA can detect plasma DNMT1 at levels as low as 10−7 U mL−1, also it successfully evaluated tumor burden and predicted the neoadjuvant therapy responses of breast cancer patients.
Yingran Wang   +10 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

open access: yesHepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah   +2 more
wiley   +1 more source

Low-Grade and High-Grade Invasive Ductal Carcinomas of the Breast Follow Divergent routes of Progression

open access: yesCancer Biology & Medicine, 2011
Low-grade invasive ductal carcinoma is almost diploid, and has frequent losses of chromosome 16q, which is shared by other precancerous lesions of the mammary gland such as flat epithelial atypia (FEA), atypical ductal hyperplasia (ADH), and low-nuclear ...
Yun NIU, Estifanos P.GEBREAMLAK
doaj   +1 more source

National Institutes of Health State-of-the-Science Conference statement: Diagnosis and Management of Ductal Carcinoma In Situ September 22-24, 2009.

open access: yesJournal of the National Cancer Institute, 2010
OBJECTIVE To provide health-care providers, patients, and the general public with a responsible assessment of currently available data on the diagnosis and management of ductal carcinoma in situ (DCIS). PARTICIPANTS A non-Department of Health and Human
C. Allegra   +13 more
semanticscholar   +1 more source

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