Results 281 to 290 of about 221,113 (351)

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

open access: yesVIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai   +11 more
wiley   +1 more source

Potential clinical utility of small extracellular vesicles derived from head and neck tumours

open access: yesVIEW, EarlyView.
Small extracellular vesicles (EVs) carry selective protein cargoes that reflect tumour cell status, making them valuable for biomarker discovery. This study compared EV proteomes from head and neck cancer (HNC) tumour tissue, saliva and plasma. Over 60% of proteins were shared across all sources, with enrichment in cancer‐related pathways such as ...
Abolfazl Jangholi   +6 more
wiley   +1 more source

Quality of Life Among Patients With Ductal Carcinoma In Situ.

open access: yesJAMA Netw Open
Dunsmore VJ   +17 more
europepmc   +1 more source

Data from Clinical Proteomics Reveals Vulnerabilities in Noninvasive Breast Ductal Carcinoma and Drives Personalized Treatment Strategies

open access: gold
Georgia Mitsa   +8 more
openalex   +1 more source

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

open access: yesVIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang   +22 more
wiley   +1 more source

Cause-specific mortality after a diagnosis of ductal carcinoma in situ: Associations with screening and socio-economic status. [PDF]

open access: yesInt J Cancer
Schmitz RSJM   +8 more
europepmc   +1 more source

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