Results 31 to 40 of about 221,113 (351)

An atypical presentation of infiltrating ductal carcinoma

open access: yesJournal of Family Medicine and Primary Care, 2016
A 64-year-old African-American female presented with nonbloody nipple discharge. Clinical and cytological examination of the discharge was normal. The mammography suggested pleomorphic calcification in the left breast. A stereotactic biopsy showed ductal
Kunal Kishor Jha, Suresh Kumar Gupta
doaj   +1 more source

Collision of ductal adenocarcinoma and neuroendocrine tumor of the pancreas: a case report and review of the literature [PDF]

open access: yes, 2017
Background: Simultaneous occurrence of exocrine and neuroendocrine tumors of the pancreas is very infrequent. We report a patient with an endocrine tumor in the pancreatic-duodenal area and extensive exocrine carcinoma involving the whole pancreas.
Blandamura, Stella   +6 more
core   +2 more sources

Down-regulation of C35 decreased the cell viability and migration of breast ductal carcinoma cells.

open access: yesPLoS ONE, 2017
BackgroundResistance to human epidermal growth factor receptor-2 (HER2)-targeted therapies is common, and results in treatment failure and new tumor progression.
Wen Che, Yun Bao, Feng Tang
doaj   +1 more source

Neutrophil gelatinase-associated lipocalin (NGAL) predicts response to neoadjuvant chemotherapy and clinical outcome in primary human breast cancer [PDF]

open access: yes, 2012
In our previous work we showed that NGAL, a protein involved in the regulation of proliferation and differentiation, is overexpressed in human breast cancer (BC) and predicts poor prognosis.
Arnold, Norbert   +18 more
core   +2 more sources

Breast: Ductal carcinoma [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Classification Invasive ductal carcinoma is a heterogeneous group with many different subtypes, some of them extremely rare. Each of these variants is associated with another pathological presentation and with a different prognosis compared to invasive ductal carcinoma of no special type (NST).
Moelans, CB, van, Diest PJ
openaire   +3 more sources

Nipple discharge: the state of the art [PDF]

open access: yes, 2019
Over 80% of females experience nipple discharge during their life. Differently from lactational (milk production) and physiological (white, green, or yellow), which are usually bilateral and involving multiple ducts, pathologic nipple discharge (PND ...
Panzironi, Giovanna   +2 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Invasive Lobular Carcinoma of the Breast with Extracellular Mucin- A New Rare Variant [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Historically, extracellular mucin secretion is by default a feature of ductal carcinoma. Lobular carcinoma is known to be associated with only intracytoplasmic mucin production and signet ring cells.
Vaibhav Bhika Bari   +2 more
doaj   +1 more source

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors. [PDF]

open access: yes, 2016
Aberrant Hedgehog (Hh)/glioma-associated oncogene (GLI) signaling has been implicated in cancer progression. Here, we analyzed GLI1, Sonic Hedgehog (Shh) and NF-κB expression in 51 breast cancer (ductal carcinoma) tissues using immunohistochemistry ...
Bei, R.   +13 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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