Results 61 to 70 of about 1,818,460 (375)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Fine needle aspiration cytology findings of mucinous carcinoma of breast: a study of eight cases with histological correlation

Journal of Pathology of Nepal, 2012
Background: Pure mucinous carcinoma is a rare histologic type of mammary neoplasm and may exist as mixed mucinous-ductal carcinoma. This study aims to describe fine needle aspiration cytology features of mucinous carcinoma of breast diagnosed in ...
RC Adhikari, A Jha
doaj   +1 more source

Outcomes and prognostic factors in parotid gland malignancies: A 10-year single center experience. [PDF]

, 2019
Objectives:To describe a 10-year single center experience with parotid gland malignancies and to determine factors affecting outcomes. Study Design:Retrospective review.
Bulbul, Mustafa, Deschler, Daniel G, Emerick, Kevin S, Khawaja, Ayaz, Lee, Hang, Lin, Derrick T, Parikh, Anuraag S, Puram, Sidharth V, Rocco, James W, Sethi, Rosh KV, Srikanth, Priya, Tjoa, Tjoson, Varvares, Mark A   +12 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

The clinical behavior of mixed ductal/lobular carcinoma of the breast: a clinicopathologic analysis

World Journal of Surgical Oncology, 2010
Background To date, the clinical presentation and prognosis of mixed ductal/lobular mammary carcinomas has not been well studied, and little is known about the outcome of this entity. Thus, best management practices remain undetermined due to a dearth of
Dunnington Gary, Banisaeed Nassim, Paruchuri Lakshmi P, Suryadevara Aparna, Rao Krishna A   +4 more
doaj   +1 more source

Readmissions and complications in breast ductal carcinoma in situ: A retrospective study comparing screen- and non-screen-detected patients

Women's Health, 2020
Objective: Population-wide mammographic screening programs aim to reduce breast cancer mortality. However, a broad view of the harms and benefits of these programs is necessary to favor informed decisions, especially in the earliest stages of the disease.
Julieta Politi, María Sala, Laia Domingo, María Vernet-Tomas, Marta Román, Francesc Macià, Xavier Castells   +6 more
doaj   +1 more source

Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma

Nature Communications, 2022
Progression from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) remains poorly understood. Here, the authors analyse over 2700 micro-dissected samples using transcriptomics to identify genes that characterise different stages of DCIS ...
Clare A. Rebbeck, Jian Xian, Susanne Bornelöv, Joseph Geradts, Amy Hobeika, Heather Geiger, Jose Franco Alvarez, Elena Rozhkova, Ashley Nicholls, Nicolas Robine, Herbert K. Lyerly, Gregory J. Hannon   +11 more
doaj   +1 more source

Continued observation of the natural history of low-grade ductal carcinoma in situ reaffirms proclivity for local recurrence even after more than 30 years of follow up

Modern Pathology, 2014
Opportunities to study the natural history of ductal carcinoma in situ are rare. A few studies of incompletely excised lesions in the premammographic era, retrospectively recognized as ductal carcinoma in situ, have demonstrated a proclivity for local ...
M. Sanders, P. Schuyler, J. Simpson, D. Page, W. Dupont   +4 more
semanticscholar   +1 more source

Can high-frequency ultrasound predict metastatic lymph nodes in patients with invasive breast cancer? [PDF]

, 2004
Aim To determine whether high-frequency ultrasound can predict the presence of metastatic axillary lymph nodes, with a high specificity and positive predictive value, in patients with invasive breast cancer.
Clough, G.R., Haigh, L.I.G., Truscott, J.   +2 more
core   +2 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source