Results 61 to 70 of about 221,113 (351)

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

FNAC Versus Core Needle Biopsy: A Comparative Study in Evaluation of Palpable Breast Lump [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Breast carcinoma is the most common malignant tumour and the leading cause of carcinoma death in women in world. The main purpose of FNAC or CNB of breast lumps is to confirm cancer preoperatively and to avoid unnecessary surgery in ...
Abhijit Saha, Madhumita Mukhopadhyay, Chhanda Das, Koushik Sarkar, Ashis Kumar Saha, Diptendra Kr Sarkar   +5 more
doaj   +1 more source

Pancreatic ductal adenocarcinoma [PDF]

, 2013
A 61-year-old gentleman who lives with his wife and 20-year-old son, presented to the polyclinic with a four week history of pruritus. On examination he was found to be jaundiced and his LFTs were high.
Bezzina, Sarah, Debattista, Daniel
core  

Physiopathological Implications of 7TM Receptors [PDF]

, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Avaliação da resposta inflamatória sistêmica induzida por carcinoma ductal in situ em cadelas

Pubvet, 2018
Em tumores mamários, é comum alterações inflamatórias, causadas principalmente em neoplasias que metastatizam. Este trabalho tem por objetivo avaliar a concentração de Proteína C Reativa, correlacionada as alterações de proteínas totais e albumina em ...
Paulo Henrique , Marcel Capelini , Gustavo Lourenço , Carolina Pereira , Marcos Eufrasio Bonato , Sandriele Goes de Campos   +5 more
doaj   +1 more source

METTL1‐Mediated M7G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control

Advanced Science, EarlyView.
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang, Shuirong Lin, Yutong Zhao, Jiale Chen, Linyuan Huang, Yuyao Liu, Zixin Huang, Dongxin An, Yifan Zhang, Zimin Song, Xi Yu, Yunpeng Hua, Jing Wang, Weiwei Wang, Yu Guo, Ming Kuang, Fang Wang, Shuibin Lin, Shunli Shen   +18 more
wiley   +1 more source

Success rates of re-excision after positive margins for invasive lobular carcinoma of the breast. [PDF]

, 2019
Rates of positive margins after surgical resection of invasive lobular carcinoma (ILC) are high (ranging from 18 to 60%), yet the efficacy of re-excision lumpReceptor subtypeectomy for clearing positive margins is unknown.
Alvarado, Michael, Esserman, Laura J, Ewing, Cheryl, Fahrner-Scott, Kelly, Mukhtar, Rita A, Piper, Merisa L, Wong, Jasmine   +6 more
core  

Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8a1 and human ch13q34 [PDF]

, 2007
Serial analysis of gene expression from aggressive mammary tumors derived from transplantable p53 null mouse mammary outgrowth lines revealed significant up-regulation of Tfdp1 (transcription factor Dp1), Lamp1 (lysosomal membrane glycoprotein 1) and ...
Abba, Martín Carlos, Aldaz, Claudio Marcelo, Cai, Wei Wen, Donehower, Lawrence A., Fabris, Victoria Teresa, Hu, Yuhui, Kittrell, Frances S., Medina, Daniel, Sahin, Aysegui   +8 more
core   +1 more source

Ductal Carcinoma In Situ

Hematology/Oncology Clinics of North America
In breast cancer (BC) pathogenesis models, normal cells acquire somatic mutations and there is a stepwise progression from high-risk lesions and ductal carcinoma in situ to invasive cancer. The precancer biology of mammary tissue warrants better characterization to understand how different BC subtypes emerge.
Bychkovsky, Brittany L., Myers, Sara, Warren, Laura E. G., De Placido, Pietro, Parsons, Heather A.   +4 more
openaire   +3 more sources