Results 81 to 90 of about 2,610,836 (314)

Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breast [PDF]

, 2014
Background: The Sloane Project is the largest prospective audit of ductal carcinoma in situ (DCIS) worldwide, with over 12000 patients registered between 2003 and 2012, accounting for 50% of screen-detected DCIS diagnosed in the UK over the period of ...
,, Ball, Graham, Clements, Karen, Dobson, Hilary, Evans, Andrew, Hanby, Andrew, Lawrence, Gill, Maxwell, Anthony, Pinder, Sarah E, Thomas, Jeremy, Thompson, Alastair, Wallis, Matthew   +11 more
core   +1 more source

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

Advanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare, Kshama Kundu, Papiya Dey, Krupa Thankam Philip, Nitish Chauhan, Muskan Sharma, Sankarsingh Kesharsingh Rajput, Birija Sankar Patro   +7 more
wiley   +1 more source

Protein expression of c-erbB-2 and p53 in normal ducts, ductal carcinoma in situ and invasive carcinoma of the same breast

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Breast cancer is thought to derive from progressively aberrant, non-invasive breast lesions, but it is not known exactly how invasive breast cancer develops from these lesions.
Marcus Vinicius Martins de Menezes, Anna Letícia Oliveira Cestari, Orlando Almeida, Marcelo Alvarenga, Glauce Aparecida Pinto, Maria Salete Costa Gurgel, Gustavo Antônio de Souza, Luiz Carlos Zeferino   +7 more
doaj   +1 more source

Diagnostic pitfall in a case of ductal carcinoma-in situ with microinvasion

Journal of Cytology, 2016
We report a case of microinvasive carcinoma of the breast cytologically diagnosed as ductal carcinoma - in situ in an 80-year-old lady with a breast lump. Extensive sampling of mastectomy specimen showed ductal carcinoma in situ (DCIS). Many ducts showed
Yasmin A Momin, Medha P Kulkarni, Bhakti D Deshmukh, Kalpana R Sulhyan   +3 more
doaj   +1 more source

A Juvenile Female with Ductal Carcinoma In situ Arising from a Fibroadenoma

Journal of Cancer Research and Practice, 2023
Ductal carcinoma in situ (DCIS) and atypical ductal hyperplasia are rare in teenagers. We report an incidental finding of DCIS in a 17-year-old girl who presented with a mass in the right breast. The pathology confirmed lower-grade DCIS in a fibroadenoma.
Wan-Yu Hung, Chih-Ling Lee, Chin-Yao Lin
doaj   +1 more source

Tumor-Infiltrating Lymphocytes (TILs) and Risk of a Second Breast Event After a Ductal Carcinoma in situ

Frontiers in Oncology, 2020
Women with a diagnosis of ductal carcinoma in situ (DCIS) have a high risk of developing a second breast event (SBE). The immune system might play a role in trying to prevent a SBE.
A. Farolfi, E. Petracci, L. Serra, A. Ravaioli, S. Bravaccini, S. Ravaioli, M. Tumedei, P. Ulivi, M. Canale, M. Puccetti, F. Falcini, S. Folli, A. Curcio, A. Rocca   +13 more
semanticscholar   +1 more source

Unusual case of Paget disease of the nipple diagnosed by nipple scraping cytology [PDF]

, 2020
Paget disease of the nipple is a rare presentation of breast cancer. It is sometimes mistaken for a benign skin condition of the nipple and surrounding areola, which can significantly delay the diagnosis and treatment.
Herbst, Ewa, McIntosh, Violet Merle, Tismenetsky, Mikhail   +2 more
core   +1 more source

Breast cancer risk and imprinting methylation in blood [PDF]

, 2015
Date of Acceptance: 17/08/2015 Acknowledgements This study was supported by the Breast Cancer Campaign (2008MayPR46) and Fraserburgh Moonlight Prowl Breast Cancer Charity. PH, GH and GWH acknowledge the support of the Scottish Government.
Haggarty, Paul, Harrison, Kristina, Heys, Steven D, Hoad, Gwen, Horgan, Graham W, Scott, Paula, Simpson, Louise, Smyth, Elizabeth   +7 more
core   +1 more source

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source

Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma

Nature Communications, 2022
Progression from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) remains poorly understood. Here, the authors analyse over 2700 micro-dissected samples using transcriptomics to identify genes that characterise different stages of DCIS ...
Clare A. Rebbeck, Jian Xian, Susanne Bornelöv, Joseph Geradts, Amy Hobeika, Heather Geiger, Jose Franco Alvarez, Elena Rozhkova, Ashley Nicholls, Nicolas Robine, Herbert K. Lyerly, Gregory J. Hannon   +11 more
doaj   +1 more source