Results 131 to 140 of about 2,641 (299)

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

open access: yesCancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang   +6 more
wiley   +1 more source

Performance of Mixed Flow Multiblade Fan as Small Duct Fan

open access: yesTRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series B, 1997
OGAWA, Takenori   +3 more
openaire   +3 more sources

Introduced dung beetles suppress methane emissions from cattle dung and alter the temporal dynamics of greenhouse gas flux Los escarabajos peloteros introducidos suprimen las emisiones de metano del estiércol de ganado y alteran la dinámica temporal del flujo de gases de efecto invernadero Besouros coprófagos introduzidos suprimem as emissões de metano do esterco bovino e alteram a dinâmica temporal do fluxo de gases de efeito estufa

open access: yesEcological Entomology, EarlyView.
Dung beetles suppressed cumulative methane flux from cattle dung by 85% and reduced total greenhouse gas emissions by 18%. Beetle activity accelerated initial CO2 release but did not alter total cumulative flux. N2O and NH3 fluxes were transient and not consistently driven by beetle presence.
Jean Holley   +2 more
wiley   +1 more source

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