Results 21 to 30 of about 14,849 (239)

Selected aspects of due diligence of sovereigns

open access: yesCopernican Journal of Finance & Accounting, 2013
The purpose of this paper is to present and analyse the prevailing credit rating methodologies, as an element of due diligence process of countries, in the light of the attributes of the sovereigns and associated risks.
Sebastian Hyżyk
doaj   +3 more sources

Due Diligence in Digital Profiling of a Counterparty

open access: yesТехника и технология пищевых производств, 2023
Economic entities involved in food production interact with a large number of counterparties and depend on their integrity. They have to check their potential business partners before cooperating.
Svetlana М. Bychkova   +2 more
doaj   +1 more source

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel   +15 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Curbing “Dark” Activity at Sea: The Role of the Marine Insurance Industry

open access: yesEuropean Journal of Risk Regulation
Some fishing vessels breach maritime laws by operating with their mandatory tracking systems (Automatic Identification System (AIS)) switched off. Marine insurers act as enablers of this practice since these vessels cannot operate without insurance. This
Priyal Bunwaree
doaj   +1 more source

Exploring traditional due diligence processes in South Africa

open access: yesJournal of Economic and Financial Sciences, 2018
The effectiveness of due diligence (DD) processes, and whether they contribute to merger and acquisition (M&A) success or failure, is an ongoing debate in auditing and assurance research. This article contributes to the debate by examining traditional DD
Adnan Patel
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Experiments to Enhance Public Real Estate in Italy: the Case of the FIP Fund

open access: yesTechne, 2012
The Italian State’s real estate is involved in a boundary definition process which is still in progress. The experiments in process and the comparison between Public Administration and private operators often focus the debate on issues which relate to ...
Andrea Ciaramella
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Representation of Older Adult Patients in Clinical Trials

open access: yesClinical and Translational Science
Older adults remain significantly underrepresented in clinical trials. This is concerning because age‐associated physiological changes can alter drug pharmacokinetics and pharmacodynamics.
Sebastian Haertter   +5 more
doaj   +1 more source

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