Results 51 to 60 of about 86,870 (259)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Associações entre besouros escarabeíneos e mamíferos de médio e grande porte da Mata Atlântica em Santa Catarina, Brasil [PDF]
, 2014 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Ecologia, Florianópolis, 2014.Os escarabeíneos estão ecológica e evolutivamente ligados aos mamíferos já que se alimentam e ...
Bogoni, Juliano André
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Finding Superior Returns in Green Portfolios: Evidence from Singapore REITs
Journal of Sustainable Real Estate, 2019 We measure the proportion of green real estate in the asset portfolios of publicly traded real estate investments trusts (REITs) in Singapore (SREITs) using the Green Mark certification. We find that the portfolio greenness of SREITs increased from 3% in
Joseph T.L. Ooi, Dang D.Q. Dung
doaj +1 more source
Removal Rates of Native and Exotic Dung by dung Beetles (Scarabaeidae: Scarabaeinae) in a Fragmented Tropical Rain Forest [PDF]
, 2010 Many studies have evaluated the effect of forest fragmentation on dung beetle assem- blage structure. However, few have analyzed how forest fragmentation affects the processes carried out by these insects in tropical forests where their food sources ...
Mario Enrique Favila Castillo +1 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Besouros indicadores (Coleoptera, Scarabaeinae) na avaliação de alteração ambiental em fragmentos de Mata Atlântica contíguos a cultivos de milho convencional e transgênico [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em EcologiaOs besouros da subfamília Scarabaeinae (Coleoptera: Scarabaeidae) são organismos extremamente importantes no ...
Campos, Renata Calixto
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source