Results 91 to 100 of about 114,155 (318)
Lactobacillus reuteri inhibition of Enteropathogenic Escherichia coli adherence to human intestinal epithelium [PDF]
Enteropathogenic Escherichia coli (EPEC) is a major cause of diarrheal infant death in developing countries, and probiotic bacteria have been shown to provide health benefits in gastrointestinal infections.
Bartman+42 more
core +2 more sources
Mesenteric thrombosis: An unusual complication of severe acute pancreatitis—Report of two cases
Abstract The incidence of acute pancreatitis is 34 per 100 000 people in the general population and is on the rise. Approximately 15% to 20% of all patients experience severe pancreatitis, with a mortality rate nearing 20%. This condition is often linked to vascular complications, although mesenteric thrombosis is a rare presentation.
Asya Zubillaga‐Mares+5 more
wiley +1 more source
Association of coeliac disease and thyroid disorders [PDF]
A case study is presented. This involves a woman who presented with features of hyperthyroidism, which were refractory to conventional therapy. She was eventually diagnosed to have co-existing coeliac disease and eventually improved on a diet excluding ...
Sciberras, Robert
core
Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang+3 more
wiley +1 more source
ABSTRACT The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) by inhibiting the iron exporter ferroportin in target cells, causing hypoferremia. Under acute inflammation, hepcidin induction requires hemojuvelin (Hjv), a bone morphogenetic protein co‐receptor, while Fpn mRNA is also suppressed in a hepcidin‐
Siqi Liu+3 more
wiley +1 more source
ABSTRACT Pathogenic germline variants in the APC gene result in familial adenomatous polyposis (FAP) which can escalate into colon cancer. Standard clinical testing failed to identify pathogenic variants in a 4‐generation FAP family. We identified and assessed co‐segregation of a 5′ untranslated region (UTR) variant, NM_001127511.3 (APC) c.‐40G>A ...
Brendon Young+9 more
wiley +1 more source
DomainScope: A disease network based on protein domain connections [PDF]
Protein domains are highly conserved functional units of proteins. Because they carry functionally significant information, the majority of the coding disease variants are located on domains. Additionally, domains are specific units of the proteins that can be targeted for drug delivery purposes.
arxiv
Gastrointestinal cancer screening and surveillance programmes : a worldwide perspective : part 2 [PDF]
Part 1 of this article can be found through this link: https://www.um.edu.mt/library/oar//handle/123456789/12879Part 2 of this article. Cancer is a leading cause of death worldwide and such deaths are projected to continue to rise, creating ...
Gerada, Jurgen
core +2 more sources
Epidemiology of Peptic Ulcer Disease: Endoscopic Results of a Systematic Investigation in Iran [PDF]
BACKGROUND Peptic ulcer disease is a multifactorial health problem affecting almost all populations worldwide. Large scale population-based studies are crucial to understanding its scope and specifications in various nations.
برازنده, فرهاد+5 more
core
DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging. [PDF]
Background & aimsThe epithelia of the intestine and colon turn over rapidly and are maintained by adult stem cells at the base of crypts. Although the small intestine and colon have distinct, well-characterized physiological functions, it remains ...
Coppola, Giovanni+5 more
core