Results 151 to 160 of about 62,975 (261)

Mechanistic Insights Into Hepatotoxicity‐Induced Liver Cirrhosis and Anemia: Iron Dysregulation, the Hepcidin–Ferroportin Axis, and Emerging Therapeutic Strategies

open access: yesOrgan Medicine, EarlyView.
Patients with alcohol‐associated liver cirrhosis or acetaminophen (APAP) toxicity frequently develop anemia with iron metabolism disturbances. Dysregulation of hepcidin–ferroportin signaling, along with inflammation, oxidative stress, hypoxia, impaired intestinal iron absorption, malnutrition, and gastrointestinal bleeding, contributes to anemia ...
Debabrata Dash, Raj Kumar Koiri
wiley   +1 more source

The Gallstone That Wouldn't Budge: From Bouveret Syndrome to Duodenal Necrosis. [PDF]

open access: yesACG Case Rep J
Kalsi H   +5 more
europepmc   +1 more source

Radiotherapy and Immunotherapy In Hepatocellular Carcinoma: Priming the Tumor Immune Microenvironment From Bench To Bedside

open access: yesPrecision Radiation Oncology, EarlyView.
The dual immunomodulatory network of radiotherapy in hepatocellular carcinoma. Radiotherapy initiates its effects by inducing immunogenic cell death and DNA double‐strand breaks. Immune Activation: Cytosolic DNA from damaged cells activates the cGAS‐STING pathway, triggering IRF3/NF‐κB‐mediated type I interferon production. This enhances dendritic cell
Zhigang Fu   +4 more
wiley   +1 more source

Small‐Scale Magnetic Soft Robots for Medical Applications: From Laboratory to Clinical Use

open access: yesSmartBot, EarlyView.
Small‐scale magnetic soft robots are emerging as promising platforms for minimally invasive diagnosis and therapy in complex in vivo environments. This review compares untethered and tethered medical magnetic robots in parallel across five translational stages, from basic performance testing to clinical evaluation.
Xingxing Ke   +29 more
wiley   +1 more source

Identification and Discrimination of Sulfated and Unsulfated Gut‐Hormone Biomarkers in Human Serum by Nanopore

open access: yesSmall, EarlyView.
This study discriminates between sulfated and unsulfated cholecystokinin‐8 gut‐hormone forms at single‐molecule‐level resolution. Using an aerolysin nanopore embedded in a hybrid lipid‐polymer membrane, the system produces distinct electrical signatures enabling highly sensitive detection, even in 20% human serum.
Luca Iesu   +3 more
wiley   +1 more source

Enteropathy produced in mice by intergenerational transmission of small intestinal microbiota from undernourished children. [PDF]

open access: yesNat Microbiol
Pruss KM   +20 more
europepmc   +1 more source

Short‐Term Surgical Outcomes of Palliative Gastrectomy According to the Extent of Lymph Node Dissection: A Nationwide Propensity Score–Weighted Cohort Analysis

open access: yesWorld Journal of Surgery, EarlyView.
The appropriate extent of lymph node dissection (LND) during palliative gastrectomy (PALG) for stage IV gastric cancer remains undefined. This study evaluated short‐term surgical outcomes of limited versus extended LND in PALG. ABSTRACT Purpose The appropriate extent of lymph node dissection (LND) during palliative gastrectomy (PALG) for stage IV ...
Sang‐Ho Jeong   +5 more
wiley   +1 more source

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