Results 171 to 180 of about 26,163 (275)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Development of a virtual phantom for HDR cervical cancer brachytherapy: A multi‐institutional tool for training, quality assurance, and variability reduction

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 6, June 2026.
Background High‐dose‐rate brachytherapy (HDR‐BT) is a critical modality in the treatment of cervical cancer, requiring accurate and efficient treatment planning. Unlike external beam radiation therapy, HDR‐BT demands specialized skills and training.
Kotaro Iijima   +10 more
wiley   +1 more source

Molecular Analysis of Biliary Tract Neoplasms Associated with Familial Adenomatous Polyposis. [PDF]

open access: yesJ Anus Rectum Colon
Shiraishi T   +11 more
europepmc   +1 more source

Cross‐anatomical evaluation of a deep‐learning auto‐contouring system: qualitative, geometric, and dosimetric validation

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 6, June 2026.
Abstract Background Accurate and consistent delineation of target and normal structures is essential for safe and effective radiotherapy. Compared with manual or atlas‐based methods, deep learning‐based auto‐contouring has demonstrated improved efficiency and reduced interobserver variability. However, its performance can vary across anatomical regions
Sara Endo   +4 more
wiley   +1 more source

Smartly Assembled near‐Micron RF‐Responsive Agents Bridge Transarterial Embolization and Immunothermal Potentiation

open access: yesAdvanced Science, Volume 13, Issue 31, 4 June 2026.
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu   +12 more
wiley   +1 more source

Acute Upper Gastrointestinal Bleeding is Associated With Poor Prognosis in Patients With Biliary Tract Cancer

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Aim Upper gastrointestinal bleeding (UGIB) is associated with an unfavorable outcome in cancer patients. In patients with biliary tract cancer (BTC), data on the incidence, management, and prognostic implications of UGIB are limited. This study investigated the prevalence, treatment efficacy, and prognostic factors associated with UGIB in BTC.
Jan Christoph Schumacher   +8 more
wiley   +1 more source

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