Results 41 to 50 of about 451,572 (294)

Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT

Advanced Science, EarlyView.
Zinc activates the ZNG1‐METAP1 complex to elevate intracellular SAM levels, which promotes PRMT5‐mediated symmetrical dimethylation of AKT at R391 and R15. This epigenetic modification facilitates AKT membrane translocation and mTORC2 activation, thereby enhancing epithelial proliferation and gut barrier integrity.
Chuanjiang Cai, Yining Zheng, Bo Sun, Guoyan Wang, Pengfei Li, Huijun Geng, Rongnuo Li, Miaomiao Zhu, Yuanyuan Zhu, Dingping Feng, Lei Chen, Guiyan Chu, Lu Deng, Shiyan Qiao   +13 more
wiley   +1 more source

Is Helicobacter pylori Infection the Primary Cause of Duodenal Ulceration or a Secondary Factor? A Review of the Evidence

Gastroenterology Research and Practice, 2013
Helicobacter pylori (H. pylori) has a role in the multifactorial etiology of peptic ulcer disease. A link between H. pylori infection and duodenal ulcer disease is now established.
Vikram Kate, N. Ananthakrishnan, Frank I. Tovey   +2 more
doaj   +1 more source

A history of gastrectomy is a risk factor for choledocholithiasis in patients undergoing cholecystectomy: A single center retrospective study

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study suggests that gastrectomy is a risk factor for choledocholithiasis. Especially in terms of the differences in reconstruction methods, the median time from gastrectomy to development of choledocholithiasis was 5.5 years for Roux‐en‐Y, which was significantly faster than 20 years for Billroth I and 35 years for Billroth II ...
Yuki Matsui, Daisuke Hashimoto, So Yamaki, Kazuki Matsumura, Hidetaka Miyazaki, Yuji Ikeda, Denys Tsybulskyi, Thanh Sang Nguyen, Sohei Satoi   +8 more
wiley   +1 more source

Морфологічні особливості виразки дванадцятипалої кишки у дітей в залежності від тяжкості захворювання та наявності Н. Pylori інфекції = Morphological features of duodenal ulcer in children, depending on the severity of the disease and the presence of H. Pylori infection

Journal of Education, Health and Sport, 2016
Dudnyk V. M., Buglova N. O. Морфологічні особливості виразки дванадцятипалої кишки у дітей в залежності від тяжкості захворювання та наявності Н. Pylori інфекції = Morphological features of duodenal ulcer in children, depending on the severity of the ...
V. M. Dudnyk, N. O. Buglova
doaj   +3 more sources

CHRONIC DUODENAL ULCER [PDF]

Journal of the American Medical Association, 1915
In the presidential address delivered before the American Surgical Association in 1900, Dr. Robert F. Weir 1 called attention to the surgical possibilities of ulcer in the duodenum. In his masterly presentation of the subject he dealt chiefly with the acute cases, especially those in which perforation had taken place.
openaire   +2 more sources

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

Advanced Intelligent Systems, EarlyView.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang, Dingsi Xiang, Shengli Mi, Jiajun Huang   +3 more
wiley   +1 more source

Characterizing the Healthcare Utilization and Costs of Hereditary Hemorrhagic Telangiectasia

American Journal of Hematology, EarlyView.
ABSTRACT Hereditary hemorrhagic telangiectasia (HHT) is the second‐most common inherited bleeding disorder worldwide, afflicting one in 4000–5000 people, and is the most morbid inherited bleeding disorder of women. HHT causes recurrent severe epistaxis, chronic gastrointestinal bleeding, heavy menstrual bleeding, and arteriovenous malformations in the ...
Hanny Al‐Samkari, Tracy J. Mayne, Misty Troutt, Hemant Patle, Marianne Clancy, Eric Duhaime   +5 more
wiley   +1 more source

Perforated duodenal ulcer in the third trimester of pregnancy

Saudi Journal of Medicine and Medical Sciences, 2015
Perforated duodenal ulcer during pregnancy is rare. We report a case of 20-year-old woman who developed perforated duodenal ulcer in the third trimester of pregnancy. Surgical repair was performed with good outcome.
Fasika Amdeslasie, Yibrah Berhe, Tewelde T Gebremariam   +2 more
doaj   +1 more source

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

Emergent transcatheter arterial embolization for norovirus‐associated life‐threatening ulcer bleeding to achieve successful hemostasis in 2‐year‐old boy

Acute Medicine & Surgery, 2016
Case We report a 2‐year‐old boy with duodenal ulcer with active bleeding that occurred as a result of norovirus gastroenteritis. On admission, the patient presented with shock accompanied with vomiting and melena.
Wakato Matsuoka, Noriyuki Kaku, Yuichiro Hirata, Sooyoung Lee, Tomohiko Akahoshi, Hiroshi Sugimori, Makoto Hayashida, Ryota Souzaki, Norihiro Fujita, Yoshiki Asayama, Tomoaki Taguchi, Hidetoshi Takada, Yoshihiko Maehara   +12 more
doaj   +1 more source