Results 161 to 170 of about 258,672 (312)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Transferability and Reproducibility of the HepaRG CometChip Assay

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT This interlaboratory evaluation of HepaRG CometChip was conducted to assess transferability and reproducibility of this new approach methodology (NAM) across four laboratories. Concentrations inducing up to ~70% relative cytotoxicity were determined by the organizing laboratory, and frozen chemical formulation blocks were sent to each ...
Leslie Recio, Carol Swartz, Lincoln Martin, Emily Rottinger, Stefan Pfuhler, Erica Pinkus, Daniel J. Roberts, Leon F. Stankowski, Simran Kaushal, Norah A. Owiti, Bevin P. Engelward   +10 more
wiley   +1 more source

PRIMARY CARCINOMA OF THE DUODENUM REPORT OF FIFTEEN VERIFIED CASES

, 1925
George B. Eusterman, David Berkman, Theodore S. Swan   +2 more
openalex   +2 more sources

Multiple Strategies for Recombinant Expression of Human Chymotrypsinogen C in Pichia Pastoris

Food Bioengineering, EarlyView.
Human chymotrypsin C (CTRC), a food‐processing protease, was expressed in Pichia pastoris via three strategies: replacing the AOX1 promoter with HpHMD, rDNA locus‐based gene integration, and engineering the pro2M mutant to evade host protease degradation. The pro2M showed 3.3‐fold higher specific activity (54.84 U/mg) and improved secretion relative to
Yi Liu, Yu Xie, Xingyu Shen, Shihui Wang, Yi Xiong, Guimin Zhang   +5 more
wiley   +1 more source

Adenocarcinoma arising from a heterotopic pancreas in the first portion of the duodenum: a case report [PDF]

, 2020
Teruya Minami, Takuro Terada, Takeshi Mitsui, Yasuni Nakanuma   +3 more
openalex   +1 more source

Metabolomic Profiling of Probiotic Lactobacillus acidophilus Strain LA01 on Bovine Bone Powder Fermentation

Food Chemistry International, EarlyView.
Probiotic Lactobacillus acidophilus strain LA01 was applied to bone powder fermentation. The adsorbable calcium, small peptides, and compounds with lipid‐lowering and antioxidant properties were greatly enriched. This study provided insights into the metabolism of probiotic fermentation and laid the scientific basis for development of value‐added ...
Ruijie Zhang, Yangfan Hu, Wenqing Wang, Bo Yu   +3 more
wiley   +1 more source

Image-Enhanced Magnified and Capsule Endoscopic Characterization of Pseudomelanosis Duodeni

GE: Portuguese Journal of Gastroenterology, 2021
Vincent Zimmer, Kai Emrich, Siegfried Exner   +2 more
doaj   +1 more source

Endoscopic resection of signet ring cell carcinoma of the duodenal bulb. [PDF]

Oxf Med Case Reports
Oura R, Katayama Y, Fujimoto Y, Kobori I, Ban S, Tamano M.   +5 more
europepmc   +1 more source

Effect of Ca level on 65Zn absorption at the ligated duodenal loop of rat.

, 1989
Hiromi Gunshin, Hiroshi Naito, Tadashi NOGUCHI, TODORIKlHidemi, Takashi Akamatsu   +4 more
openalex   +2 more sources

Mechanisms of Action Involved in the In Vivo Gastroprotective Response of Fruits: A Systematic Review

Food Frontiers, EarlyView.
ABSTRACT Gastrointestinal diseases remain a significant global health concern, primarily due to the limitations of current pharmacological treatments, which often come with adverse side effects and high recurrence rates. This situation highlights the urgent need for safer and more effective alternatives.
Isabel Sousa Alcântara, Renata Torres Pessoa, Lucas Yure Santos da Silva, Tarcisio Mendes Silva, Isis Oliveira Menezes, Anita Oliveira Brito Pereira Bezerra Martins, Irwin Rose Alencar de Menezes, Almir Gonçalves Wanderley   +7 more
wiley   +1 more source