Results 161 to 170 of about 405,743 (404)
British Journal of Clinical Pharmacology, EarlyView.Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia +4 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.Dash and coworkers have fabricated a small intestine on a chip, which encapsulates the physiology and biofilm of the small intestinal epithelium. The dynamic system showed villus differentiation within 5 days of flow, and the mucus layer and biofilm showed small intestinal characteristics.
Sanat Kumar Dash +2 more
wiley +1 more source
DEN OpenA 70‐year‐old woman presented to our hospital with abdominal discomfort. Gastrointestinal endoscopy revealed an ampullary tumor, while a biopsy revealed a pathological diagnosis of adenocarcinoma.
Koji Takahashi +8 more
doaj +1 more source
Chemical Impacts of the Microbiome Across Scales Reveal Novel Conjugated Bile Acids [PDF]
, 2019 A mosaic of cross-phyla chemical interactions occurs between all metazoans and their microbiomes. In humans, the gut harbors the heaviest microbial load, but many organs, particularly those with a mucosal surface, associate with highly adapted and ...
Mazmanian, Sarkis +2 more
core
PERFORATED ULCER OF THE DUODENUM. *1WITH REPORT OF 14 CASES [PDF]
, 1906 S MAYNARDSMITH
openalex +1 more source
Expression of IRBIT Along the Rat Gastrointestinal Tract [PDF]
, 2020 IRBIT (inositol-1,4,5-trisphosphate (IP3) receptors binding protein released with IP3) regulates fluid transport in the pancreatic duct and other epithelial cells.
Bazaldua, Amanda +3 more
core +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
BMEMat, EarlyView.This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu +7 more
wiley +1 more source
A Relation-Centric Query Engine for the Foundational Model of Anatomy [PDF]
, 2004 The Foundational Model of Anatomy (FMA), a detailed representation of the structural organization of the human body, was constructed to support the development of software applications requiring knowledge of anatomy.
Ann Li +9 more
core +4 more sources
Introducing Novel Surgical Clinical Correlations Into an Undergraduate Medical Anatomy Course
Clinical Anatomy, EarlyView.ABSTRACT Anatomy education is a hallmark of many preclinical medical school curricula, but students are often unable to identify the clinical relevance of anatomy and its applications. Vertical curricula that integrate clinical concepts into the preclinical basic science years and vice versa have been shown to benefit student learning and increase ...
Liam McLoughlin +5 more
wiley +1 more source