Results 191 to 200 of about 149,629 (303)

The Gut–Brain Axis in Parkinson's Disease: From Clinical Observation toward Mechanism‐Based Precision Medicine

Movement Disorders, EarlyView.
Abstract Gastrointestinal dysfunction is increasingly recognized as a core feature of Parkinson's disease (PD), affecting quality of life, nutrition, medication response, and potentially the earliest stages of pathogenesis. This perspective traces the evolution of the gut from a neglected source of non‐motor symptoms to a central component of ...
Filip Scheperjans, Per Borghammer, Ronald F. Pfeiffer, Silke Appel‐Cresswell, Ali Keshavarzian   +4 more
wiley   +1 more source

Serotonin- and Somatostatin-Positive Goblet Cell Carcinoid of the Duodenum

In the duodenum, mixed exocrine-endocrine tumors exhibiting both neuroendocrine and glandular differentiations [cf. appendiceal goblet cell carcinoids (GCCs)] are rare.
Kaga, Hitoshi, Tominaga, Susumu, Okusa, Yasushi, Ogawa, Tomomichi, Ohara, Ichiyou, Ogata, Sho, Hase, Kazuo, Niihara, Naoko, Matsuzaki, Koji   +8 more
core  

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Pyloric Pseudonecrosis Caused by Biliary Peritonitis: A Rare Intraoperative Pitfall. [PDF]

Clin Case Rep
Mouawad C, Eid D, Dager N.
europepmc   +1 more source

Improving enteral nutrition in patients requiring neurological intensive care unit care: A retrospective study on a novel bedside nasointestinal tube placement technique

Nutrition in Clinical Practice, EarlyView.
Abstract Background This study aimed to develop and assess a bedside nasojejunal tube placement technique designed for resource‐limited settings to address the specific challenges of enteral nutrition (EN) delivery in neurocritical care patients, particularly those at high risk of reflux and aspiration. The technique sought to overcome the drawbacks of
Niuchenglin, Liujuan, Zhushuibing, Dingyuanliang, Yutianhao, Shiguangling   +5 more
wiley   +1 more source

A Gallstone Masquerading as Hepatic Decompensation: A Case of Bouveret Syndrome. [PDF]

Cureus
Nadendla L, Vijayaraghavan S.
europepmc   +1 more source

Extreme Obesity (BMI ≥ 60 kg/m2) Characterization up to and Beyond 80 kg/m2 in 1,262,454 Bariatric Surgery Patients

Obesity, EarlyView.
ABSTRACT Objective This study aimed to estimate extreme obesity prevalence and association with disease burden and outcomes in patients undergoing metabolic and bariatric surgery (MBS). Methods Cross‐sectional data from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP, 2015–2023) were analyzed (n = 1,795,127 ...
Vance L. Albaugh, Hector Garcia Navas, Robert C. Ross, Florina Corpodean, Michael Kachmar, Denise M. Danos, Steven B. Heymsfield, Peter Katzmarzyk, Michael W. Cook, Philip R. Schauer   +9 more
wiley   +1 more source

Plant‐Derived Bioactives and PPAR Signaling in Functional Dyspepsia: Mechanistic Insights and Therapeutic Perspectives

Phytotherapy Research, EarlyView.
Functional dyspepsia involves duodenal barrier dysfunction, low‐grade immune activation and altered neuroimmune signalling. Various plant‐derived bioactives may modulate PPAR signalling, reduce inflammatory and oxidative stress, and support epithelial, immune, metabolic, and sensory homeostasis.
Irene Palenca, Emidio Scarpellini, Jan Tack, Pierluigi De Pierro, Giovanni Sarnelli, Giuseppe Esposito   +5 more
wiley   +1 more source

A DIVERTICULUM OF THE DUODENUM [PDF]

BMJ, 1933
openaire   +2 more sources