Results 291 to 300 of about 259,733 (360)

Peptidomics in Different Phases of Severe Acute Pancreatitis Model

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Severe acute pancreatitis (SAP) involves dynamic shifts from inflammation to immunosuppression, where peptidomic profile evolution may reveal prognostic biomarkers. Here, the plasma peptidome of rats with taurocholate‐induced SAP at 1, 3, 6, 12, and 24 h compared with controls was characterized using nLC‐MS/MS.
Roberto Rasslan, Marcia Kiyomi Koike, Marcel Cerqueira Cesar Machado, Luiz Felipe Martucci, Leo Kei Iwai, Rosangela Aparecida dos Santos Eichler, Edivaldo Massazo Utiyama, Emer Suavinho Ferro, Edna Frasson de Souza Montero   +8 more
wiley   +1 more source

Online adaptive MR-guided SBRT versus CT-based planning in pancreatic cancer: A single-center dosimetric comparative study. [PDF]

J Appl Clin Med Phys
Kamel R, Gevaert T, Van den Berge D, De Ridder M.   +3 more
europepmc   +1 more source

Impact of Obesity and MASH on Zonal Hepatocellular Statin Exposure: Pharmacodynamic Insights From a Permeability‐Limited Multicompartment Liver Model

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Obesity, MASH and Statins: Insights from a PBPK/PD Zonal Liver Model. ABSTRACT Statins are frequently prescribed for hyperlipidemia, a common comorbidity in patients with obesity and/or metabolic dysfunction‐associated steatohepatitis (MASH). However, limited knowledge exists on how MASH may alter statin disposition within hepatocytes where the statin ...
William A. Murphy, Noora Sjöstedt, Mailys De Sousa Mendes, Mattie Hartauer, Kim L. R. Brouwer, Sibylle Neuhoff   +5 more
wiley   +1 more source

Improved PTV coverage and OAR sparing with stereotactic MRI-guided online adaptive radiotherapy with elective fields in pancreatic cancer. [PDF]

Tech Innov Patient Support Radiat Oncol
Konnerth D, Hojo H, Fuchs F, Shouman MA, Dehelean DC, Gaasch A, Walter F, Eze C, Marschner SN, Mansoorian S, Maier SH, da Silva Mendes V, Hofmaier J, Niyazi M, Belka C, Corradini S, Rogowski P.   +16 more
europepmc   +1 more source

SPECTRUM OF HELICOBACTER PYLORI IN HUNDRED PATIENTS PRESENTING WITH PERFORATED DUODENAL ULCER

, 2011
Iqbal Haider, Dildar Hussain, Ali Muhammmad   +2 more
openalex   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates, Michael Zientek, Kunal S. Taskar, Wen Lin, Tycho Heimbach, Stefan Willmann, Jessica Rehmel, Neil Parrott, Michael Hanley, Justine Badee, Yuan Chen, Susan Cole, Loeckie De Zwart, Sebastian Haertter, Rongrong Jiang, Masakatsu Kotsuma, Guiqing Liang, Yu‐Wei Lin, Jing Liu, Ying Ou, Juliane Rascher, Naveed A. Shaik, Jan Wahlstrom, Xiaofeng Wang, Guangqing Xiao, Ka Lai Yee, S. Y. Amy Cheung   +26 more
wiley   +1 more source

Gene cloning of S100β and NGF and localization of their expression in the small intestine of broilers of various ages. [PDF]

Sci Rep
Han R, Tian X, Xu C, Qi F.
europepmc   +1 more source

Adenoma of the duodenum

Journal of British Surgery, 1951
openaire   +2 more sources

Beyond Pathology: α‐Synuclein Homeostasis and Three Principles to Guide Research

Movement Disorders Clinical Practice, EarlyView.
Alberto J. Espay, Andrew J. Lees
wiley   +1 more source

From Radiocopper to Cold Copper: Mechanistic Modeling and Simulation to Define Clinical Response Criteria and Biomarkers for VTX‐801 in Wilson Disease

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT We developed a comprehensive, mechanistic model of human copper metabolism to support biomarker qualification for VTX‐801, an adeno‐associated vector‐based gene therapy which is being developed to restore the mutated ATP7B copper transporter gene in Wilson disease (WD). The model integrates physiological copper kinetics with pathophysiological
Andreas Lindauer, Bernard Benichou, Gloria González Aseguinolaza, Jean‐Philippe Combal   +3 more
wiley   +1 more source