Results 31 to 40 of about 20,527 (318)

Reduction in hospitalisations with dupilumab in Japanese adults with atopic dermatitis in a real‐world setting

open access: yesJEADV Clinical Practice, 2023
Background In a recent post hoc analysis of multinational clinical trial data, dupilumab treatment for patients with moderate or severe atopic dermatitis (AD) reduced all‐cause and AD‐related hospitalisations.
Ken Igawa   +6 more
doaj   +1 more source

Impact of exacerbation history on long-term efficacy of dupilumab in patients with asthma

open access: yesERJ Open Research, 2023
Background The phase 3 QUEST (NCT02414854) and TRAVERSE (NCT02134028) studies demonstrated the efficacy of dupilumab 200/300 mg versus placebo every 2 weeks for 52 weeks (QUEST) and dupilumab 300 mg up to an additional 96 weeks (TRAVERSE) in patients ≥12 
Jonathan Corren   +12 more
doaj   +1 more source

Dupilumab: A new paradigm for the treatment of allergic diseases [PDF]

open access: yes, 2018
Moderate and severe forms of allergic diseases such as atopic dermatitis and asthma are a challenge for clinicians. In these conditions, which severely affect the quality of life of the patient and frequently have associated allergic comorbidities, the ...
Dávila, Ignacio, Sastre, Joaquín
core   +2 more sources

Facial redness in Japanese adolescents with atopic dermatitis treated with dupilumab: A case series

open access: yesJournal of Allergy and Clinical Immunology: Global, 2023
This case series study is the first report of Japanese adolescents who experienced dupilumab facial redness after starting dupilumab treatment for refractory atopic dermatitis.
Shuhei Hara, MD   +5 more
doaj  

Conjunctivitis in patients with atopic dermatitis treated with dupilumab

open access: yesDrugs in Context, 2020
Atopic dermatitis (AD) is a common, chronic, inflammatory skin disorder with high physical and emotional burden. Robust evidence suggests that interleukin (IL)-4 and IL- 13 are key cytokines in the immunopathogenesis of AD.
Sandra Ferreira, Tiago Torres
doaj   +1 more source

Two‐sided influence of dupilumab on alopecia areata co‐existing with severe atopic dermatitis: A case series and literature review

open access: yesJournal of Cutaneous Immunology and Allergy, 2023
Objectives Alopecia areata (AA) often coexists with atopic dermatitis (AD). Recently, several reports suggested that dupilumab, an interleukin 4 receptor α‐antagonist, administration could be a promising medication not only for severe AD but also for AA ...
Masahiro Fukuyama   +3 more
doaj   +1 more source

Cicatricial ectropion in a patient treated with dupilumab

open access: yesAmerican Journal of Ophthalmology Case Reports, 2017
Purpose: To describe a case of bilateral conjunctivitis and cicatricial ectropion associated with dupilumab therapy for atopic dermatitis. Observations: Severe hyperemia of the conjunctiva and eyelid margins, as well as cicatricial ectropion, began two ...
Alexander C. Barnes   +2 more
doaj   +1 more source

Severe Atopic Dermatitis In Spain: A Real-Life Observational Study [PDF]

open access: yes, 2019
Objective: To determine the epidemiology and characterize the treatment prescribed for severe atopic dermatitis (AD) in children/adults in usual clinical practice.
Armario Hita, José Carlos   +2 more
core   +2 more sources

Dupilumab-associated cicatrizing ocular disease

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: To describe three cases of bilateral cicatrizing conjunctivitis associated with dupilumab treatment for atopic dermatitis. Observations: Case 1 is a 69 year-old male with a history of mild, stable cicatrizing conjunctivitis thought to be ...
Amit K. Reddy   +4 more
doaj  

Efficacy and Safety of Dupilumab in Moderate-to-Severe Bullous Pemphigoid

open access: yesFrontiers in Immunology, 2021
BackgroundBullous pemphigoid (BP) is an autoimmune blistering disorder that predominantly affects the elderly. As the main treatment for BP, systemic corticosteroids are often limited by their side effects. Safer treatment modalities are therefore needed.
Yihua Zhang   +7 more
doaj   +1 more source

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