FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Identifying and Analyzing Bot-Generated Responses in Online Health Care Surveys: Methodological Study. [PDF]
JMIR Med InformHamovitch E, McKellar K, Wodchis WP.
europepmc +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Comment on Rastogi et al. Brain Tumor Detection and Prediction in MRI Images Utilizing a Fine-Tuned Transfer Learning Model Integrated Within Deep Learning Frameworks. <i>Life</i> 2025, <i>15</i>, 327. [PDF]
Life (Basel)Pastore EP.
europepmc +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
CHO Cell-Produced Truncated Bovine Ephemeral Fever Virus Glycoprotein as a Promising Subunit Vaccine Candidate for Cattle. [PDF]
Vaccines (Basel)Hsu HY, Yeh SJ, Chen CC, Ke GM.
europepmc +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Great Bay Estuary Tidal Tributary Monitoring Program (GBETTMP) 2013-2017 Quality Assurance Project Plan [PDF]
, 2013 New Hampshire Department of Environmental Services +1 more
core +1 more source
Prevalence Trends and Antimicrobial Resistance of Carbapenem-Resistant Gram-Negative Bacteria in Paediatric Patients in Sichuan Province: A Retrospective Study (2021-2025). [PDF]
Infect Drug ResistYou Z, Huang X, Liu X, Yu H, Long S.
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source