Mechanisms of gene duplication and translocation and progress towards understanding their relative contributions to animal genome evolution [PDF]
, 2012 Duplication of genetic material is clearly a major route to genetic change, with consequences for both evolution and disease. A variety of forms and mechanisms of duplication are recognised, operating across the scales of a few base pairs upto entire ...
Mendivil Ramos, Olivia +1 more
core +1 more source
Cell Reports, 2019 Summary: Progression of DNA replication depends on the ability of the replisome complex to overcome nucleoprotein barriers. During eukaryotic replication, the CMG helicase translocates along the leading-strand template and unwinds the DNA double helix ...
Hazal B. Kose +3 more
doaj +1 more source
Investigation of human centrosomes - with a special focus on the function of Cep152 and Cep192 in centriole duplication [PDF]
, 2012 Centrioles are symmetrical, barrel-shaped, microtubule-based structures, that serve as building platforms for the formation of centrosomes and cilia. In dividing cells, they recruit a matrix of proteins called pericentriolar material (PCM) to form the ...
Sonnen, Katharina Friederike
core +1 more source
On the regulation of centriole duplication in human cells : exploring the interactions of polo-like kinase 4 with the centrosomal proteins Cep192 and STIL [PDF]
, 2015 Centrioles duplicate once in each cell cycle to give rise to two centrosomes that form the spindle poles during mitosis. Aberrant centriole duplication can result in the formation of supernumerary centrosomes, leading to incorrect spindle assembly and ...
Gabryjonczyk, Anna-Maria
core +1 more source
Plants, 2020 The autophagy-related genes (ATGs) play important roles in plant growth and response to environmental stresses. Brassica napus (B. napus) is among the most important oilseed crops, but ATGs are largely unknown in this species.
Elham Mehri Eshkiki +4 more
doaj +1 more source
Laparoscopic Partial Gastrectomy of a Huge Gastric Duplication Cyst in an Infant [PDF]
, 2015 2015-02Gastric duplication cyst is a rare anomaly, and most cases are recognized during childhood. Recently, several pediatric cases with small gastric duplication cysts treated by laparoscopic resection have been reported. Here, we describe an infant in
UCHIDA, HIROO +6 more
core +1 more source
Total Colonic Tubular Duplication Including Terminal Ileum and Appendix: A Rare Case [PDF]
, 2021 Total colonic duplications are rare. This case is reported here in order to discuss the treatment of tubular duplication of the entire colon, appendix and terminal ileum. A 2-year-old girl was admitted with complaints of vomiting, abdomen distension, and
Mehmet Saraç +3 more
core +1 more source
Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region [PDF]
, 2012 Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functional
Gagneux, Sebastian +93 more
core +1 more source
Acute abdomen secondary to complete tubular colonic duplication
Journal of Indian Association of Pediatric Surgeons, 2014 We report the case of a 6-month-old infant who presented with a complete duplication of the large intestine, debuting clinically with acute abdomen and severe metabolic disorders.
Javier Castejón-Casado +5 more
doaj +1 more source
Frontiers in Plant Science, 2020 BZR transcription factors play essential roles in plant growth and environmental stimuli, and they are also the positive regulators of Brassinosteroid (BR) signal transduction in diverse plants. In addition, BZR TFs, as crucial regulators of BR synthesis,
Yunpeng Cao +7 more
doaj +1 more source