Results 11 to 20 of about 1,522,266 (144)

In Vivo Assembly of Artificial Metalloenzymes and Application in Whole-Cell Biocatalysis*. [PDF]

open access: yesAngew Chem Int Ed Engl, 2021
Artificial metalloenzymes were created by supramolecular assembly in the cytoplasm of E. coli cells. The cells were then applied to the enantioselective biocatalysis of a Friedel–Crafts alkylation of indoles (see picture) and a Diels–Alder reaction. Directed evolution of the artificial metalloenzymes inside the cells provided improved variants for both
Chordia S   +4 more
europepmc   +3 more sources

Prediction of outcome after ligation or thin film banding of extrahepatic shunts, based on plasma albumin concentration and hematologic expression of 8 target genes in 85 dogs. [PDF]

open access: yesJ Vet Intern Med, 2023
Abstract Background In dogs with a congenital extrahepatic portosystemic shunt (EHPSS), outcome after surgical attenuation is difficult to predict. Objectives Develop a minimally invasive test to predict outcome after surgical EHPSS attenuation and establish risk factors for postattenuation seizures (PAS). Animals Eighty‐five client‐owned dogs referred
van Blokland-Post K   +5 more
europepmc   +2 more sources

The Predictive Forward-Forward Algorithm [PDF]

open access: yesAnnual Meeting of the Cognitive Science Society, 2023
We propose the predictive forward-forward (PFF) algorithm for conducting credit assignment in neural systems. Specifically, we design a novel, dynamic recurrent neural system that learns a directed generative circuit jointly and simultaneously with a ...
Alexander Ororbia, A. Mali
semanticscholar   +1 more source

SNARF: Differentiable Forward Skinning for Animating Non-Rigid Neural Implicit Shapes [PDF]

open access: yesIEEE International Conference on Computer Vision, 2021
Neural implicit surface representations have emerged as a promising paradigm to capture 3D shapes in a continuous and resolution-independent manner. However, adapting them to articulated shapes is non-trivial.
Xu Chen   +4 more
semanticscholar   +1 more source

Transformer Feed-Forward Layers Are Key-Value Memories [PDF]

open access: yesConference on Empirical Methods in Natural Language Processing, 2020
Feed-forward layers constitute two-thirds of a transformer model’s parameters, yet their role in the network remains under-explored. We show that feed-forward layers in transformer-based language models operate as key-value memories, where each key ...
Mor Geva   +3 more
semanticscholar   +1 more source

Scaling Forward Gradient With Local Losses [PDF]

open access: yesInternational Conference on Learning Representations, 2022
Forward gradient learning computes a noisy directional gradient and is a biologically plausible alternative to backprop for learning deep neural networks.
Mengye Ren   +3 more
semanticscholar   +1 more source

From terrible twos to sassy sixes: The development of vocabulary and executive functioning across early childhood

open access: yesDevelopmental Science, Volume 26, Issue 6, November 2023., 2023
Abstract Across the early childhood period of development, young children exhibit considerable growth in their executive functioning (EF) and vocabulary abilities. Understanding the developmental trajectory of these seemingly interrelated processes is important as both early vocabulary and EF have been shown to predict critical academic and socio ...
Madeleine Bruce   +2 more
wiley   +1 more source

Middle childhood attachment‐based family therapy: Theory and model description

open access: yesFamily Process, Volume 62, Issue 3, Page 1040-1054, September 2023., 2023
Abstract In middle childhood, the first manifestations of mental health problems can emerge and become a precursor of mental health issues in adolescence. Given that weak parent–child attachment can contribute to this distress, it is possible that strengthening the attachment bond could reduce risk trajectory.
Leen Van Vlierberghe   +2 more
wiley   +1 more source

Educational interventions involving physical manipulatives for improving children's learning and development: A scoping review

open access: yesReview of Education, Volume 11, Issue 2, August 2023., 2023
Abstract Physical manipulatives (PMs) are concrete objects used during hands‐on learning activities (e.g., building blocks, fraction tiles, counters), and are widely used in primary‐school teaching, especially during maths instruction. This scoping review collated studies that have examined the effectiveness of educational PM interventions with pre ...
Elizabeth M. Byrne   +3 more
wiley   +1 more source

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