Results 71 to 80 of about 48,725 (263)

Collagenase clostridium histolyticum for the treatment of Dupuytren's contracture: systematic review and economic evaluation.

Health Technology Assessment, 2015
BACKGROUND Dupuytren's disease is a slowly progressive condition of the hand, characterised by the formation of nodules in the palm that gradually develop into fibrotic cords. Contracture of the cords produces deformities of the fingers.
M. Brazzelli, M. Cruickshank, Emma Tassie, Paul McNamee, C. Robertson, A. Elders, C. Fraser, R. Hernández, D. Lawrie, C. Ramsay   +9 more
semanticscholar   +1 more source

Intrasheath Tendon Subluxation Beyond the Ankle

Journal of Ultrasound in Medicine, Volume 44, Issue 12, Page 2361-2369, December 2025.
Peroneal tendon intrasheath subluxation is a well‐established phenomenon in musculoskeletal ultrasound. However, until now, intrasheath tendon subluxation has not been described in the hand. This unique case series presents the first three reported cases of intrasheath tendon subluxation in the hand.
Hannah Lamberg, Molly N. Pantelic, Erika Mojica, Heidi Ehrich, Dana Rowland, Shannon Wood, Gunjan Malhotra, Steven B. Soliman   +7 more
wiley   +1 more source

Хирургическая коррекция сгибательной контрактуры суставов пальцев кисти при болезни Дюпюитрена [PDF]

, 2009
ДЮПЮИТРЕНА КОНТРАКТУРАКИСТЬОРТОПЕДИЯТРАВМАТОЛОГИЯСОЕДИНИТЕЛЬНОЙ ТКАНИ БОЛЕЗНИДЮПЮИТРЕНА БОЛЕЗНЬВ основу исследования положена разработка дифференцированного подхода к хирургической коррекции сгибательной контрактуры суставов пальцев кисти с целью ...
Дейкало, В. П., Толстик, А. Н.   +1 more
core  

Peyronie's disease in the United States: A real‐world, 13‐year nationwide analysis of demographics, clinical characteristics, and treatment trends

Andrology, Volume 13, Issue 8, Page 2265-2272, November 2025.
Abstract Background Real‐world data on Peyronie's disease remains limited. Objectives Describe the demographics, clinical characteristics, and therapeutic management of Peyronie's disease patients in the United States. Materials and methods A retrospective analysis was conducted using the PearlDiver Mariner database (2010–2022).
Angelo Orsini, Eugenio Bologna, Gabriele Bignante, Francesco Lasorsa, Luca Lambertini, Arianna Biasatti, Giovanni Liguori, Michele Marchioni, Francesco Porpiglia, Giuseppe Lucarelli, Luigi Schips, Davide Arcaniolo, Marco De Sio, Edward E. Cherullo, Riccardo Autorino, Celeste Manfredi   +15 more
wiley   +1 more source

Collagenase clostridium histolyticum in patients with Dupuytren’s contracture: results from POINT X, an open-label study of clinical and patient-reported outcomes

Journal of Hand Surgery (European Volume), 2015
In POINT X, a study designed to reflect clinical practice and patient treatment choices, 254 European patients received open-label collagenase for Dupuytren’s contracture. The most severely affected joint was treated first in 74% of patients.
D. Warwick, M. Arner, G. Pajardi, B. Reichert, Z. Szabó, E. Masmejean, J. Forés, D. Chapman, R. Gerber, F. Huard, A. Seghouani, P. Szczypa   +11 more
semanticscholar   +1 more source

Identification of histological patterns in clinically affected and unaffected palm regions in dupuytren's disease. [PDF]

PLoS ONE, 2014
Dupuytren's disease is a fibro-proliferative disease characterized by a disorder of the extracellular matrix (ECM) and high myofibroblast proliferation. However, studies failed to determine if the whole palm fascia is affected by the disease.
Camilo-Andrés Alfonso-Rodríguez, Ingrid Garzón, Juan Garrido-Gómez, Ana-Celeste-Ximenes Oliveira, Miguel-Ángel Martín-Piedra, Giuseppe Scionti, Giuseppe Scionti, Víctor Carriel, Pedro Hernández-Cortés, Antonio Campos, Miguel Alaminos   +10 more
doaj   +1 more source

Identification of Novel Craniofacial Regulatory Domains Located far Upstream of SOX9 and Disrupted in Pierre Robin Sequence. [PDF]

, 2014
Mutations in the coding sequence of SOX9 cause campomelic dysplasia (CD), a disorder of skeletal development associated with 46,XY disorders of sex development (DSDs). Translocations, deletions, and duplications within a ∼2 Mb region upstream of SOX9 can
Abadie, V., Amiel, J., Ansari, M., Attanasio, C., Benko, S., Bhatia, S., FitzPatrick, D., Goldenberg, A., Gordon, C.T., Kleinjan, D.A., Lyonnet, S., Munnich, A., Pennacchio, L.A., Tan, T.Y., Temple, I.K., van Heyningen, V., Visel, A.   +16 more
core   +3 more sources

Limited progression of subclinical Dupuytren's disease:results from a prospective cohort study [PDF]

, 2021
AIMS: With novel promising therapies potentially limiting progression of Dupuytren's disease (DD), better patient stratification is needed. We aimed to quantify DD development and progression after seven years in a population-based cohort, and to ...
Broekstra, Dieuwke C., van den Berge, Bente A., Werker, Paul M.N.   +2 more
core   +1 more source

Collagenase treatment does not impair fiber contractile function in muscle biopsies from children with cerebral palsy

Physiological Reports, Volume 13, Issue 21, November 2025.
Abstract Cerebral palsy (CP) often presents with increased passive stiffness of the skeletal muscles, primarily due to increased collagen in the extracellular matrix. Collagenase from Clostridium histolyticum (CCH), an enzyme that degrades collagen, is used clinically to treat fibrotic conditions such as Dupuytren's contracture and Peyronie's disease ...
Faizan Syed, Latif Omerkhil, Venus Joumaa, Jason J. Howard, Timothy R. Leonard, Walter Herzog   +5 more
wiley   +1 more source

Dupuytren’s Contracture in Athletes

Quality in Sport
Background. Dupuytren’s contracture is a fibrotic condition of the hand, traditionally associated with age, genetics, and metabolic factors. However, recent observations suggest it may also appear in younger individuals with high physical activity ...
Tomasz Antczak, Monika Gajda-Bathelt , Monika Dąbek, Katarzyna Jania, Zuzanna Perlicka , Karolina Smolińska , Paulina Sadkowska , Julia Kulczycka , Weronika Popow , Michał Ciołkosz   +9 more
doaj   +1 more source