Results 21 to 30 of about 2,851 (150)

Dupuytren’s interventions surgery versus collagenase (DISC) trial: study protocol for a pragmatic, two-arm parallel-group, non-inferiority randomised controlled trial

Trials, 2021
Background Dupuytren’s contracture is a fibro-proliferative disease of the hands affecting over 2 million UK adults, particularly the white, male population. Surgery is the traditional treatment; however, recent studies have indicated that an alternative
Joseph Dias, Catherine Arundel, Puvan Tharmanathan, Ada Keding, Charlie Welch, Belen Corbacho, Maria Armaou, Paul Leighton, Christopher Bainbridge, Michael Craigen, Lydia Flett, Samantha Gascoyne, Catherine Hewitt, Elaine James, Sophie James, Nick Johnson, Judy Jones, Catherine Knowlson, Priya Radia, David Torgerson, David Warwick, Michelle Watson   +21 more
doaj   +1 more source

Finger shortening for Dupuytren’s disease-induced severe PIP joint flexion contracture of the little finger: A report of two cases

SICOT-J, 2021
When severe proximal interphalangeal (PIP) joint flexion contracture is induced in the little finger by Dupuytren’s disease, it interferes with activities of daily living.
Ito Yoko, Naito Kiyohito, Nagura Nana, Sugiyama Yoichi, Obata Hiroyuki, Kaneko Ayaka, Goto Kenji, Kaneko Kazuo, Ishijima Muneaki   +8 more
doaj   +1 more source

Dupuytren’s contractures associated with the BRAF inhibitor vemurafenib: a case report [PDF]

, 2015
INTRODUCTION: Two previous cases of the development of Dupuytren’s contractures were reported in association with BRAF inhibitor treatment for BRAF V600E mutation-positive metastatic melanoma and metastatic papillary thyroid carcinoma.
Daniel Alberto Vorobiof, Sze Wai Chan
core   +1 more source

Dupuytren's Contracture Cosegregation with Limb-Girdle Muscle Dystrophy

Case Reports in Neurological Medicine, 2013
Limb-girdle muscular dystrophies (LGMDs) is a heterogeneous group of muscular dystrophies that mostly affect the pelvic and shoulder girdle muscle groups.
Baiba Lace, Inna Inashkina, Ieva Micule, Inta Vasiljeva, Maruta Solvita Naudina, Jurgis Strautmanis, Janis Stavusis, Eriks Jankevics   +7 more
doaj   +1 more source

Surgery for Dupuytren’s contracture of the fingers (Review) [PDF]

, 2015
Background - Dupuytren's disease is a benign fibroproliferative disorder that causes the fingers to be drawn into the palm via formation of new tissue under the glabrous skin of the hand. This disorder causes functional limitations, but it can be treated
Ball, C, Becker, GW, Davies, T, Giele, H, Hobby, J, Pratt, AL, Rodrigues, JN, Zhang, W   +7 more
core   +1 more source

A Complete Expression Profile of Matrix-Degrading Metalloproteinases in Dupuytren’s Disease [PDF]

, 2007
Dupuytren’s disease (DD) is a common fibrotic condition of the palmar fascia, leading to deposition of collagen-rich cords and finger contractions. The metzincin superfamily contains key enzymes in the turnover of collagen and other extracellular matrix ...
Adrian J. Chojnowski, Baker, Baragi, Bird, Bisson, Bretz, Brinckerhoff, Brown, Bunker, Clark, Daniels, Drummond, d’Ortho, Graham P. Riley, Hutchinson, Ian M. Clark, Iredale, Jones, Jung, Kashiwagi, Kevorkian, Knauper, Le Goff, Luck, Mikkelsen, Mirastschijski, Moyer, Murphy, Nuttall, Ohuchi, Phillip Johnston, Porter, Porter, Price, Qian, Rayan, Rose K. Davidson, Schaer, Scott, Simon T. Donell, Smith, Tarlton, Tarpila, Thurston, Ulrich, Unemori, Unemori, Unemori, Williams   +48 more
core   +1 more source

Night time splinting without surgery for dupuytren’s contracture – a successful case series of elderly diabetic patients

Liaquat Medical Research Journal, 2022
Dupuytren’s contracture is a musculoskeletal deformity mainly involves fingers of the hands. Elderly diabetic patients more frequently suffer from the problem.
Asim Niaz Channa, Sana Shahzad, Faisal Jamil   +2 more
doaj   +1 more source

Types and stages of vascular remodeling in Dupuytren's contracture (analysis of 506 arteries in the surgical material of 111 patients) [PDF]

Гений oртопедии, 2020
Purpose Analysis of the severity and staging of pathomorphological changes in the arteries of palmar aponeurosis in patients with Dupuytren's contracture of different age groups Materials and methods Analysis of case records of patients younger than 50 ...
Natalia A. Shchudlo, Tatyana N. Varsegova, Tatyana A. Stupina, Mikhail M. Shchudlo   +3 more
doaj   +1 more source

The role of mast cells in the progression of Dupuytren's contracture

Гений oртопедии, 2023
Introduction World literature data indicate the involvement of mast cells in the pathogenesis of Dupuytren's disease. There is no information on the content of mast cells in the pathologically altered palmar fascia of patients depending on the severity ...
Natalia A. Shchudlo, Tatyana A. Stupina, Tatyana N. Varsegova, Daria A. Ostanina   +3 more
doaj   +1 more source

Connective tissue degeneration: Mechanisms of palmar fascia degeneration (Dupuytren’s disease) [PDF]

, 2016
Dupuytren’s disease is a connective tissue disorder of the hand causing excessive palmar fascial fibrosis with associated finger contracture and disability.
Chojnowski, A., Clark, I., Dorjée, A. L., Karkampouna, S., Kloen, P., Kreulen, M., Kruithof-de Julio, Marianna, Obdeijn, M. C., Rivellese, F.   +8 more
core   +1 more source