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Dupuytren’s disease. State of the art and therapeutic perspectives
Dupuytren’s disease is a benign fibroproliferative disorder characterised by the sclerosis and the retractile thickening of the medial palmar aponeurosis and digital aponeurosis, which can lead to the progressive and irreversible finger flexion. Genetic,
F.P. Cantatore, A. Corrado
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Systematic review of non-surgical treatments for early Dupuytren’s disease [PDF]
Introduction There is no approved treatment for early Dupuytren’s disease (DD) to prevent progression of flexion deformities requiring subsequent treatment with invasive procedures.
Catherine Ball +4 more
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A Complete Expression Profile of Matrix-Degrading Metalloproteinases in Dupuytren’s Disease [PDF]
Dupuytren’s disease (DD) is a common fibrotic condition of the palmar fascia, leading to deposition of collagen-rich cords and finger contractions. The metzincin superfamily contains key enzymes in the turnover of collagen and other extracellular matrix ...
Adrian J. Chojnowski +48 more
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Dupuytren’s disease and collagenase: evidence for a paradigm shift in management
**Introduction**: Dupuytren’s disease is a common condition that leads to significant functional impairment of the hand. The recent introduction of collagenase clostridium histolyticum as a therapeutic option has changed the approach to disease ...
Jessica A Paynter +3 more
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3-Dimensional fasciectomy: A highly efficacious common ground approach to Dupuytren’s surgery
Background Numerous Dupuytren’s fasciectomy techniques have been described, each associated with unique surgical challenges, complications and recurrence rates.
Benjamin H Miranda +6 more
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Dupuytren’s disease is a contracture of the hand derived from the retractile fibrosis of the palmar aponeurosis, that leads to a progressive deformity in flexion of fingers.
Richard Trèves
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Connective tissue degeneration: Mechanisms of palmar fascia degeneration (Dupuytren’s disease) [PDF]
Dupuytren’s disease is a connective tissue disorder of the hand causing excessive palmar fascial fibrosis with associated finger contracture and disability.
Chojnowski, A. +8 more
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Dupuytren's Contracture Cosegregation with Limb-Girdle Muscle Dystrophy
Limb-girdle muscular dystrophies (LGMDs) is a heterogeneous group of muscular dystrophies that mostly affect the pelvic and shoulder girdle muscle groups.
Baiba Lace +7 more
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Paediatric Dupuytren's disease
Dupuytren's disease of the hand has only been rarely reported in children and is rarer still in infants. Only a few histologically confirmed diagnoses are found in literature.
Pradeoth Mukundan Korambayil +1 more
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This systematic review covering publications in the Medline and Embase databases for the period 1946 to 2020 revealed a higher prevalence of Dupuytren’s disease among men exposed to vibration compared to men not exposed to vibration. The risk assessment,
Tohr Nilsson +3 more
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