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The Molecular Pathogenesis of Dupuytren Disease [PDF]
BackgroundEver since the classification of Dupuytren disease into the proliferative, involutional, and residual stages, extensive research has been performed to uncover the molecular underpinnings of the disease and develop better treatment modalities ...
Alan D. Widgerow +21 more
core +1 more source
Background:. Rasch measurement theory can be used to identify scales within questionnaires and to map responses to more precise continuous scales. The aim of this article was to use RMT to refine the scoring of the QuickDASH in patients with Dupuytren ...
Paul H.C. Stirling, MD, FRCS +4 more
doaj +1 more source
Abstract Far‐from‐equilibrium thermodynamics were studied in patients with either lung cancer or pulmonary inflammatory diseases. Histological and mechanical activities were due to myofibroblasts. A study on isolated lung fragments treated with the Huxley formalism showed that mechanical abnormalities were similar in both groups: maximum velocity ...
Yves Lecarpentier +7 more
wiley +1 more source
Uncoupling TGFβ1 signalling from collagen protein synthesis in Dupuytren's disease
Abstract Dupuytren's disease is a fibroproliferative disorder of the palmer fascia (PF) characterised by flexion contractures in the hand. Dupuytren's disease can be treated surgically, but disease recurrence rates are high, potentially due to continual production of matrisomal proteins.
Gabriella Cooper +12 more
wiley +1 more source
Molecular Genetics of Dupuytren´s Disease
Dupuytren’s disease (DD) is a fibromatosis of connective tissue within the palm of the hands. It is characterised by progressive collagen deposition that leads to hardening and thickening of the connective tissue and results in permanent contraction of ...
Becker, Kerstin
core
Wnt pathway in Dupuytren disease: connecting profibrotic signals [PDF]
A role of Wnt signaling in Dupuytren disease, a fibroproliferative disease of the hand and fingers, has not been fully elucidated. We examined a large set of Wnt pathway components and signaling targets and found significant dysregulation of 41 Wnt ...
Bank, Ruud A. +4 more
core +1 more source
Dupuytren, Guillaume, 1777-1835, prantsuse kirurgArsti ettekirjutus haigele ...
Dupuytren, Guillaume
core
Background Dupuytren disease, a chronic thickening and retraction of the palmar aponeurosis of the hands, may result in permanent and progressive flexion of one or more fingers.
Giuseppe Basile +6 more
doaj +1 more source

