Results 51 to 60 of about 197,091 (215)

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Prevalence and associated factors of postdural puncture headache in cesarean section patients following spinal anesthesia in a public hospital in Harar, Eastern Ethiopia.

PLOS Global Public Health
Post-dural puncture headache is becoming a major health problem around the globe. Even though it becomes the reason for increased maternal morbidity, there is still a great scarcity of research in Eastern Ethiopia.
Gizachew Tilaye, Alemayehu Tesfaye, Awoke Getiye, Birhanu Shegene, Mengistu Chalie, Abebe Tolera   +5 more
doaj   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Application of 3D‐Slicer combined with 3D printing technology in training neurosurgery resident physicians' imaging spatial cognition and clinical reasoning: A self‐controlled before‐ and after‐study

Anatomical Sciences Education, EarlyView.
Abstract Neurosurgical residency training requires advanced spatial cognition and 3D anatomical understanding, which traditional methods often fail to adequately develop. This study evaluated a novel educational model integrating 3D Slicer and 3D printing technology to enhance imaging spatial cognition and clinical reasoning among neurosurgery ...
Li Xueyu, Fan Yuanxian, Chen Jiaxing, Li Chuanyu, Chen Yuanbiao, Huang Haineng, Huang Huadong, Luo Kunxiang, Wei Shiyin, Tan Rong   +9 more
wiley   +1 more source

POST DURAL PUNCTURE HEADACHE: A COMPARISON OF MIDLINE AND PARAMEDIAN APPROACH OF SPINAL ANESTHESIA

Pakistan Armed Forces Medical Journal, 2020
Objective: To compare the midline and paramedian approaches of spinal anesthesia in terms of incidence of Post Dural Puncture Headache among patients undergoing surgery. Study Design: Comparative prospective study.
Zeeshan Nasir, Saira Mahboob, Tariq Mehmood, Syed Zaheer Haider   +3 more
doaj   +4 more sources

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

Transnasal sphenopalatine ganglion block for post‐dural puncture headache and associated tinnitus

Anaesthesia Reports, 2021
Lumbar epidurals are frequently inserted for women in labour as they provide excellent analgesia. One of the more common procedural complications is post‐dural puncture headache which can be associated with auditory symptoms such as hearing loss and ...
H. Chua, L. Loh, M. Mok
semanticscholar   +1 more source

Consent for anaesthesia: guidelines from the Association of Anaesthetists

Anaesthesia, EarlyView.
Summary Introduction Guidelines on consent for anaesthesia were first issued by the Association of Anaesthetists in 1999 and last revised in 2017. These new guidelines respond to the changing ethical, legal and clinical landscape in which anaesthetists practice. Since 2017, the Montgomery judgment has changed medical consent practice.
Andrew McLeod, David Bogod, James Brooks, Michael Devlin, Natalie Joseph‐Williams, Rehana Iqbal, Nadine Montgomery‐Allam, Felicity Plaat, Alex Ruck Keene, Cliff Shelton, Vinnie Sodhi, Michael Swart, Emma Wain, Hugo Wellesley, Jenny Westaway   +14 more
wiley   +1 more source

Depth of extradural space and dural puncture [PDF]

Anaesthesia, 1991
Summary The records of 3011 obstetric extradural blocks were examined to determine the depth of the extradural space and the relative risk of dural puncture. The overall incidence of dural puncture was 0.7%. A disproportionate number of punctures occurred when the space was superficial (1.45%), with a risk factor three times greater ...
D N, Sutton, S P, Linter
openaire   +2 more sources

Frequency and characteristics of multi‐domain autonomic dysfunction in patients with spontaneous intracranial hypotension

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Spontaneous intracranial hypotension (SIH) is caused by leakage of cerebrospinal fluid and often produces symptoms that worsen when standing, which may resemble autonomic disorders (conditions related to blood flow and heart rate).
Woo‐Seok Ha, Da Eun Jung, Sojung Yoon, Joonho Kim, Min Kyung Chu   +4 more
wiley   +1 more source