Results 101 to 110 of about 9,046,003 (326)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Temporal and Spatial Characteristics of Tidal Current in the Eastern Waters of Macao in Summer

open access: yesRenmin Zhujiang, 2023
The eastern waters of Macao at the Pearl River Estuary are an important channel for water and sediment discharged by the west beach of Lingdingyang Estuary and Macao waterway.The measured data during the flood seasons shows that the waters feature semi ...
FANG Shenguang   +4 more
doaj  

Stage surgical and catheter approach to the treatment of long-persistent atrial fibrillation

open access: yesРоссийский кардиологический журнал, 2019
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E. A. Artyukhina   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Duration discrimination in younger and older adults [PDF]

open access: yes, 2001
Ten normal hearing young adults and ten older adults were asked to identify the longer of two sequentially presented tones. The duration of the standard tones ranged from 1.5 ms to 1000 ms across blocks.
Bergeson, Tonya R.   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Estimating Unemployment Duration [PDF]

open access: yes
macroeconomics ...
James P. Luckett
core  

Anthropogenic intensification of short-duration rainfall extremes

open access: yesNature Reviews Earth & Environment, 2021
H. Fowler   +18 more
semanticscholar   +1 more source

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