Results 81 to 90 of about 25,469,677 (308)

Estimating duration intervals [PDF]

open access: yes
Duration intervals measure the dynamic impact of advertising on sales. More precise, the p per cent duration interval measures the time lag between the advertising impulse and the moment that p per cent of its effect has decayed. In this paper, we derive
Franses, Ph.H.B.F., Vroomen, B.L.K.
core  

Antidepressant Trial Duration versus Duration of Real-World Use: A Systematic Analysis

open access: yesThe American Journal of Medicine
Abstract Importance Antidepressant use is rising globally, with increasing duration of real-world prescribing. While the FDA considers 6-8 week trials adequate for regulatory approval, guidelines recommend prolonged treatment.
William Ward   +2 more
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Duration and Risk [PDF]

open access: yes
Duration has long been used as a means of managing the risk of bond portfolios. It has also been extended to the analysis of equities. Although it is often been compared with the half-life of an asset it is more correct to consider duration as the ...
Gerald R. Brown
core  

Bayesian Analysis of Inverse Gaussian Stochastic Conditional Duration Model

open access: yesJournal of Statistical Theory and Applications (JSTA), 2019
This paper discusses Bayesian analysis of stochastic conditional duration model when the innovations follow inverse Gaussian distribution. Estimation is carried out by the methods of Markov Chain Monte Carlo.
C.G. Sri Ranganath, N. Balakrishna
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Determinants of Unemployment Duration in Russia [PDF]

open access: yes
Using information contained in a nationally representative, longitudinal survey of Russian citizens, this research analyzes the determinants of unemployment duration during the early stages of economic transition. A competing-risks, discrete-time waiting
Mark C. Foley
core  

Short-duration rainfall extremes in Sweden: a regional analysis

open access: yesHydrology Research, 2019
We investigate short-duration rainfall extremes in a 22-year long (1996–2017) time series of 15-min values from 128 stations in Sweden. Two different approaches are used to fit extreme value distributions (EVDs) to the data: generalized extreme value ...
Jonas Olsson   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Econometric analysis of financial trade processes by discrete mixture duration models [PDF]

open access: yes, 2005
We propose a new framework for modelling the time dependence in duration processes being in force on financial markets. The pioneering ACD model introduced by Engle and Russell (1998) will be extended in a manner that the duration process will be ...
Hujer, Reinhard, Vuletić, Sandra
core  

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