Results 71 to 80 of about 3,120,988 (284)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Perception of the intensity and duration of a stimulus within a unified framework: psychophysics and underlying neuronal processing [PDF]

, 2019
Every sensory experience is embedded in time, and is accompanied by the perception of the passage of time. The fact that perception of the content of a sensory event and the perception of the time occupied by that event are generated in parallel raises a
Toso, Alessandro
core  

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Stochastic variations in sensory awareness are driven by noisy neuronal adaptation: evidence from serial correlations in perceptual bistability [PDF]

, 2009
When the sensory system is subjected to ambiguous input, perception alternates between interpretations in a seemingly random fashion. Although neuronal noise obviously plays a role, the neural mechanism for the generation of randomness at the slow time ...
Physics of Man (Human Perception), Physics of Man, Sub Human Perception, van Ee, R.   +3 more
core  

The duration of economic expansions and recessions: more than duration dependence [PDF]

, 2008
One widespread idea in the business cycles literature is that the older is an expansion or contraction, the more likely it is to end. This paper tries to provide further empirical support for this idea of positive duration dependence and, at the same ...
Vitor Manuel Alves Castro, Castro, Vítor Manuel Alves   +1 more
core   +1 more source

Distortions of subjective time perception within and across senses.

PLoS ONE, 2008
BackgroundThe ability to estimate the passage of time is of fundamental importance for perceptual and cognitive processes. One experience of time is the perception of duration, which is not isomorphic to physical duration and can be distorted by a number
Virginie van Wassenhove, Dean V Buonomano, Shinsuke Shimojo, Ladan Shams   +3 more
doaj   +1 more source

Apparent Duration of Sound Perception [PDF]

The Journal of the Acoustical Society of America, 1935
With the aid of a vacuum tube “impulsator” the limits for which the integral law of apparent duration holds true, were determined; they are expressed by the value ∫t1t2 log Idt, for the extent of the apparent duration. Experiments with different impulses of tones of 1000 vib./sec., showed that the law holds true for limits of from 2 to 50 units of ...
openaire   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Tactile perception of thermal diffusivity [PDF]

, 2009
The thermal diffusivity of an object is a parameter that controls the rate at which heat is extracted from the hand when it touches that object. It is an important feature for distinguishing materials by means of touch.
Physics of Man (Human Perception), Physics of Man, Bergmann Tiest, W.M., Sub Human Perception, Kappers, A.M.L.   +4 more
core   +1 more source