Results 91 to 100 of about 6,175,850 (290)

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source

Machine Learning-Based Prediction of Dust Storms in Al-Ahsa, Saudi Arabia, Using NOAA Meteorological and MODIS Aerosol Data

Aerosol and Air Quality Research
Dust storms are a major environmental hazard in arid regions, significantly affecting air quality, public health, and infrastructure. Accurate forecasting is essential, particularly in the Middle East, where dust activity is driven by regional ...
Sarah Albugami
doaj   +1 more source

A Dual‐Mode In Situ EV‐miRNA Profiling Platform for Machine‐Learning‐Assisted Gastric Cancer Liquid Biopsy

Advanced Science, EarlyView.
An in situ dual‐mode platform integrates fusogenic liposomes with localized autocatalytic DNA circuits for plasma‐derived extracellular vesicle microRNA analysis. Following membrane fusion, target miRNAs trigger feedback‐assisted LECHA amplification inside intact vesicles, generating fluorescence and electrochemical outputs. Machine learning integrates
Wenbin Li, Rui Fan, Kun Xie, Jiehua Zhong, Yitong Zhu, Tingting Ji, Yuanyuan Qin, Shijin Peng, Yu Zhang, Yuhang Guo, Tiange Zhang, Chunchen Liu, Bo Li, Lei Zheng, Ye Zhang, Xiaohui Yan   +15 more
wiley   +1 more source

Impacts of Carbon Dioxide Deposition on Martian Near‐Surface Wave Activity

Geophysical Research Letters
A prominent feature of Mars' winter atmosphere is near‐surface baroclinic wave activity. These waves exert strong control on dust storm variability and contribute to transport of heat, momentum, and dust.
Hung Kwan Fok, Anthony Toigo, Darryn Waugh   +2 more
doaj   +1 more source

Mitigation strategies of healthcare centers for dust hazard: A systematic review

Journal of Education and Health Promotion
Exposure to dust can disrupt healthcare services and severely affect all activity domains of the health system. This study aimed to present an overview of mitigation strategies taken in healthcare centers during dust storms.
Arezoo Sarani, Asghar Tavan, Mohsen Aminizadeh, Seyed Mobin Moradi, Kambiz Bahaadinbeigy, Hojjat Farahmandnia   +5 more
doaj   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Analysis of the Effect of Climatic Parameters and Meteorological Droughts on the Variation of Internal Dust Events (A Case Study: Qazvin City)

علوم آب و خاک, 2020
The occurrence of wind erosion and the spread of dust particles can be regarded as one of the most important and threatening environmental factors. Climate change and the frequency of droughts have played an important role in exacerbating or weakening ...
S. Zandifar, Z. Ebrahimikhusfi, M. khosroshahi, M. Naeimi   +3 more
doaj  

An objective method of forecasting pre-monsoon thunderstorm dust storm activity over Delhi and neighbourhood

MAUSAM, 1972
An attempt was made to provide an objective aid for forecasting of thunderstorm/dust storm in pre-monsoon season over Delhi and neighbourhood. Relationships of a number of meteorological parameters to subsequent convective activity were determined and the five parameters which showed the strongest relation ships were combined by graphical correlation ...
openaire   +2 more sources

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source