Results 91 to 100 of about 303,702 (277)

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song   +6 more
wiley   +1 more source

Structure and Spectroscopic Characterisation of Phenanthroline‐Based Iodobismuthate(III) Complexes Utilised for Raw Acoustic Signal Classification

open access: yesAdvanced Intelligent Discovery, EarlyView.
Memristors based on trimethylsulfonium (phenanthroline)tetraiodobismuthate have been utilised as a nonlinear node in a delayed feedback reservoir. This system allowed an efficient classification of acoustic signals, namely differentiation of vocalisation of the brushtail possum (Trichosurus vulpecula).
Ewelina Cechosz   +4 more
wiley   +1 more source

Accelerating Biosensor Discovery: A Computationally‐Driven Pipeline for Microplastics Monitoring

open access: yesAdvanced Intelligent Discovery, EarlyView.
A computationally guided pipeline unites molecular simulation, synthetic biology, electrochemical engineering, and machine learning to accelerate biosensor discovery. A Bacillus anthracis carbohydrate‐binding module is used to develop a high‐performance micro‐ and nanoplastics sensor with greatly reduced error and variability.
Gabriel X. Pereira   +13 more
wiley   +1 more source

Interannual similarity in the Martian atmosphere during the dust storm season

open access: yesGeophysical Research Letters, 2016
We find that during the dusty season on Mars (southern spring and summer) of years without a global dust storm there are three large regional‐scale dust storms. The storms are labeled A, B, and C in seasonal order.
D. M. Kass   +4 more
doaj   +1 more source

Dielectric Elastomer Actuators as Safe and Effective Tools for Mechanostimulation of Human Cells

open access: yesAdvanced Intelligent Systems, EarlyView.
Replicating physiological forces is crucial for realistic cell models. Dielectric elastomer actuators (DEAs) offer a soft alternative, though their high voltages raised toxicity concerns. We demonstrate that DEA stimulation causes no cell damage, cell death or cell‐cycle disruption, while activating mechanosensitive responses.
Simon Holzer   +6 more
wiley   +1 more source

Impact of drought on dust storms: case study over Southwest Iran

open access: yesEnvironmental Research Letters, 2019
Dust storms are common meteorological events in arid and semi-arid regions, particularly in Southwest Iran (SWI). Here we study the relation between drought events in Iraq and dust storms in SWI between 2003 and 2018.
Mostafa Javadian   +2 more
doaj   +1 more source

At the edge of change: Native Phragmites persistence and nonnative arrival along the dam‐regulated Colorado River

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise The southwestern United States is at the forefront of nonnative Phragmites australis subsp. australis expansion. Native Phragmites australis subsp. americanus, likely in decline in North America, is ecologically and culturally important and of conservation interest. In the greater Grand Canyon region, the Glen Canyon Dam led to loss of
Emily C. Palmquist   +6 more
wiley   +1 more source

Mortality risks from a spectrum of causes associated with sand and dust storms in China. [PDF]

open access: yesNat Commun, 2023
Zhang C   +6 more
europepmc   +1 more source

Identification of senescence‐related genes in Parkinson's disease reveals candidate therapeutic targets and pathological processes

open access: yesAnimal Models and Experimental Medicine, EarlyView.
At the genomic level, a large number of differentially expressed genes (DEGs) and aging‐related DEGs have been screened. Ten hub genes, such as IFNγ and IRF7, have been identified and shown potential value in the diagnosis of PD, holding promise as novel biomarkers to facilitate early and precise diagnosis.
Haojie Wu   +3 more
wiley   +1 more source

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