Results 51 to 60 of about 303,702 (277)

Iterative Selection of DNA Nanostructures for Cellular Uptake

Advanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar, Lisa Eichhorn, Jakub Palacka, Sandra Ly, Erik Benson   +4 more
wiley   +1 more source

Nowcasting of dust and convective storms via diffusion-model predictions of SEVIRI RGB imagery

Weather and Climate Extremes
Convective storms in the tropics are inherently unpredictable on the scales typical of global Numerical Weather Prediction (NWP) models. Rapid-refresh short term predictions, so called nowcasts, provide added value and can improve forecasts on short ...
Kilian Hermes, John H. Marsham, Massimo Bollasina, Melissa Brooks, Martina Klose, Franco Marenco   +5 more
doaj   +1 more source

Coating‐Free Nanoscratching for Liquid‐Crystal Alignment on PCB‐Compatible Millimeter‐Wave Reflective Unit Cells

Advanced Materials Technologies, EarlyView.
Direct nanoscratching with a 500 nm diamond lapping film creates groove‐guided liquid‐crystal alignment interfaces on PCB‐compatible Cu‐patterned RF substrates within minutes, eliminating polymer coating and high‐temperature baking. The coating‐free process enables optical/molecular alignment validation and voltage‐programmable 28 GHz reflection‐phase ...
Junseok Ma, Ga‐Yeong Park, Geunjung Lee, Hyo‐Won Lee, Jong‐Won Yu, Dong Ki Yoon   +5 more
wiley   +1 more source

The MEDUSA and MicroMED Experiments for the ExoMars Space Programme to Perform In Situ Analysis of Martian Dust [PDF]

, 2011
This thesis describes the work for the PhD in Aerospace, Naval and Total Quality Management of the University of Naples “Federico II” from 2008 to 2011. The work was mostly performed at National Institute of Astrophysics (INAF) - Astronomical Observatory
Ventura, Sergio
core   +1 more source

Atmospheric controls on mineral dust emission from the Bodélé Depression, Chad: The role of the low level jet [PDF]

, 2005
Atmospheric aerosols play an important though uncertain role in the Earth's climate system. The Bodélé Depression in Chad stands out as the planet's largest source of dust, yet very little is known about the atmospheric circulation that maintain this ...
Washington, R, Richard Washington (13228215), Richard Washington, Martin C. Todd, Todd, MC, Martin Todd (4462747)   +5 more
core  

Optimizing Stratification in Binary Colloidal Supraparticles

Advanced Science, EarlyView.
Supraparticles from binary particle populations show stratification when dried at high Péclet numbers. In spray‐dried systems at high initial particle concentration and fast drying conditions optimal combinations of particle size ratios and volume fractions that produce maximal stratification are found both in experiment and simulation, contrasting the
Frederic Rudlof, Silas Wolf, Sonja Schaller, Jonathan Martín González, Carsten Schilde, Nicolas Vogel   +5 more
wiley   +1 more source

Mesoporous Catalytic‐Adsorptive Nanoregulator Orchestrates Biofilm eDNA/LPS Disassembly and TLR9/TLR4 Immune Reprogramming to Resolve Diabetic Foot Infections

Advanced Science, EarlyView.
Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song, Yang Song, Xirui Huang, Xingjin Li, Lifei Gao, Yixiang Wang, Tianbao Zhu, Xiaomin Li, Shuai Wang, Tiancong Zhao, Dongyuan Zhao   +10 more
wiley   +1 more source

Self‐Sustaining Lactate Depletion Nanoplatform Remodels Tumor Microenvironment and Augments Synergistic Photodynamic/Photothermal/Chemodynamic/Starvation Therapy for Eradication of Colon Cancer

Advanced Science, EarlyView.
The HILA nanoplatform integrates HMnO2, LOX, and ICG to orchestrate multimodal therapy (starvation, chemodynamic, photodynamic, and photothermal) for achieving efficient colon cancer eradication. The established HMnO2‐LOX catalytic cycle continuously consumes lactate, acidifys microenvironment, relieves hypoxia, and generats reactive oxygen species ...
Yu‐E. Wang, Shibo Zhao, Wenying Wu, Zhiwei Duan, Yuan Li, Xiangyu Zeng, Liang Hong, Yan Chen, Ling Tao, Kewu Zeng, Chaoda Xiao, Xiangchun Shen   +11 more
wiley   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao, Xudong Yu, Ziqian Shang, Mengyao Tan, Xie Huang, Zaizhi Du, Xiaojiao Wang, Xinrui Yang, Ximei Luo, Weidong Wang, Rong Li, Shenglin Luo   +11 more
wiley   +1 more source